L291-0018 Screening compound: N-[1-(4-tert-butylbenzoyl)piperidin-4-yl]benzenesulfonamide

L291-0018 Screening compound: N-[1-(4-tert-butylbenzoyl)piperidin-4-yl]benzenesulfonamide
L291-0018 Screening compound: N-[1-(4-tert-butylbenzoyl)piperidin-4-yl]benzenesulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L291-0018
N-[1-(4-tert-butylbenzoyl)piperidin-4-yl]benzenesulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L291-0018

Molecular Formula

C22H28N2O3S (C22 H28 N2 O3 S)

Compound Name

N-[1-(4-tert-butylbenzoyl)piperidin-4-yl]benzenesulfonamide

IUPAC name

N-[1-(4-tert-butylbenzoyl)piperidin-4-yl]benzenesulfonamide

SMILES

CC(C)(C)c(cc1)ccc1C(N(CC1)CCC1NS(c1ccccc1)(=O)=O)=O

InChI

InChI=1S/C22H28N2O3S/c1-22(2,3)18-11-9-17(10-12-18)21(25)24-15-13-19(14-16-24)23-28(26,27)20-7-5-4-6-8-20/h4-12,19,23H,13-16H2,1-3H3

InChI Key

FASKIMSDPHKRSR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27241291

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

400.54

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.201

Distribution Coefficient, logD

4.201

Water Solubility, LogSw

-4.04

Polar Surface Area

58.392

Acid Dissociation Constant (pKa)

11.28

Base Dissociation Constant (pKb)

-3.00

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.90

L291-0018 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L291-0018 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L291-0018?
Check Price and Availability of L291-0018, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L291-0018 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L291-0018
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L291-0018
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L291-0018 available by request