L291-0658 Screening compound: N-{1-[2-(1H-indol-3-yl)acetyl]piperidin-4-yl}-4-methoxybenzene-1-sulfonamide

L291-0658 Screening compound: N-{1-[2-(1H-indol-3-yl)acetyl]piperidin-4-yl}-4-methoxybenzene-1-sulfonamide
L291-0658 Screening compound: N-{1-[2-(1H-indol-3-yl)acetyl]piperidin-4-yl}-4-methoxybenzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L291-0658
N-{1-[2-(1H-indol-3-yl)acetyl]piperidin-4-yl}-4-methoxybenzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L291-0658

Molecular Formula

C22H25N3O4S (C22 H25 N3 O4 S)

Compound Name

N-{1-[2-(1H-indol-3-yl)acetyl]piperidin-4-yl}-4-methoxybenzene-1-sulfonamide

IUPAC name

N-{1-[2-(1H-indol-3-yl)acetyl]piperidin-4-yl}-4-methoxybenzene-1-sulfonamide

SMILES

COc(cc1)ccc1S(NC(CC1)CCN1C(Cc1c[nH]c2c1cccc2)=O)(=O)=O

InChI

InChI=1S/C22H25N3O4S/c1-29-18-6-8-19(9-7-18)30(27,28)24-17-10-12-25(13-11-17)22(26)14-16-15-23-21-5-3-2-4-20(16)21/h2-9,15,17,23-24H,10-14H2,1H3

InChI Key

AHWDAJSCZYBHRX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27241496

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

427.52

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.011

Distribution Coefficient, logD

3.011

Water Solubility, LogSw

-3.45

Polar Surface Area

75.279

Acid Dissociation Constant (pKa)

11.71

Base Dissociation Constant (pKb)

-0.38

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

L291-0658 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Indole Derivatives (10091 compounds)

KRAS-Targeted Library (16000 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Structure:
  • Cyclic compounds
  • Mimetics
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with L291-0658 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L291-0658?
Check Price and Availability of L291-0658, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L291-0658 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L291-0658
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L291-0658
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L291-0658 available by request