L291-0735 Screening compound: 4-methoxy-N-{1-[(2E)-3-(2-methoxyphenyl)prop-2-enoyl]piperidin-4-yl}benzene-1-sulfonamide

L291-0735 Screening compound: 4-methoxy-N-{1-[(2E)-3-(2-methoxyphenyl)prop-2-enoyl]piperidin-4-yl}benzene-1-sulfonamide
L291-0735 Screening compound: 4-methoxy-N-{1-[(2E)-3-(2-methoxyphenyl)prop-2-enoyl]piperidin-4-yl}benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L291-0735
4-methoxy-N-{1-[(2E)-3-(2-methoxyphenyl)prop-2-enoyl]piperidin-4-yl}benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L291-0735

Molecular Formula

C22H26N2O5S (C22 H26 N2 O5 S)

Compound Name

4-methoxy-N-{1-[(2E)-3-(2-methoxyphenyl)prop-2-enoyl]piperidin-4-yl}benzene-1-sulfonamide

IUPAC name

4-methoxy-N-{1-[(2E)-3-(2-methoxyphenyl)prop-2-enoyl]piperidin-4-yl}benzene-1-sulfonamide

SMILES

COc(cc1)ccc1S(NC(CC1)CCN1C(/C=C/c(cccc1)c1OC)=O)(=O)=O

InChI

InChI=1S/C22H26N2O5S/c1-28-19-8-10-20(11-9-19)30(26,27)23-18-13-15-24(16-14-18)22(25)12-7-17-5-3-4-6-21(17)29-2/h3-12,18,23H,13-16H2,1-2H3

InChI Key

RHYLMVUOELFJLK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27241546

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

430.52

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.386

Distribution Coefficient, logD

3.386

Water Solubility, LogSw

-3.89

Polar Surface Area

73.038

Acid Dissociation Constant (pKa)

11.71

Base Dissociation Constant (pKb)

2.87

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.80

L291-0735 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Covalent Inhibitors Library (7986 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
Structure:
  • Cyclic compounds
  • 3D
  • Fragments

References: we are preparing a list of scientific research reports with L291-0735 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L291-0735?
Check Price and Availability of L291-0735, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L291-0735 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L291-0735
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L291-0735
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L291-0735 available by request