L293-2489 Screening compound: 5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-methyl-N-{1-oxo-1-[4-(pyridin-2-yl)piperazin-1-yl]propan-2-yl}benzene-1-sulfonamide

L293-2489 Screening compound: 5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-methyl-N-{1-oxo-1-[4-(pyridin-2-yl)piperazin-1-yl]propan-2-yl}benzene-1-sulfonamide
L293-2489 Screening compound: 5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-methyl-N-{1-oxo-1-[4-(pyridin-2-yl)piperazin-1-yl]propan-2-yl}benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L293-2489
5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-methyl-N-{1-oxo-1-[4-(pyridin-2-yl)piperazin-1-yl]propan-2-yl}benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L293-2489

Molecular Formula

C24H28N6O4S (C24 H28 N6 O4 S)

Compound Name

5-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)-2-methyl-N-{1-oxo-1-[4-(pyridin-2-yl)piperazin-1-yl]propan-2-yl}benzene-1-sulfonamide

IUPAC name

5-(5-cyclopropyl-124-oxadiazol-3-yl)-2-methyl-N-{1-oxo-1-[4-(pyridin-2-yl)piperazin-1-yl]propan-2-yl}benzene-1-sulfonamide

SMILES

CC(C(N(CC1)CCN1c1ncccc1)=O)NS(c1c(C)ccc(-c2noc(C3CC3)n2)c1)(=O)=O

InChI

InChI=1S/C24H28N6O4S/c1-16-6-7-19(22-26-23(34-27-22)18-8-9-18)15-20(16)35(32,33)28-17(2)24(31)30-13-11-29(12-14-30)21-5-3-4-10-25-21/h3-7,10,15,17-18,28H,8-9,11-14H2,1-2H3/t17-/m0/s1

InChI Key

PUMFSLCYJNYVFF-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD27241643

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

496.59

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

3.940

Distribution Coefficient, logD

3.927

Water Solubility, LogSw

-4.02

Polar Surface Area

101.994

Acid Dissociation Constant (pKa)

9.40

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

41.70

L293-2489 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Akt-Targeted Library (14764 compounds)

Antibacterial Compounds Library (13827 compounds)

Epigenetics Focused Set (26518 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Infections
  • Immune system
  • animal
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L293-2489 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L293-2489?
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What is the minimum amount of L293-2489 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L293-2489
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L293-2489
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L293-2489 available by request