L294-0459 Screening compound: N-{4-[5-(2,4-dimethyl-1,3-thiazol-5-yl)-1,2,4-oxadiazol-3-yl]phenyl}-4-methylbenzene-1-sulfonamide

L294-0459 Screening compound: N-{4-[5-(2,4-dimethyl-1,3-thiazol-5-yl)-1,2,4-oxadiazol-3-yl]phenyl}-4-methylbenzene-1-sulfonamide
L294-0459 Screening compound: N-{4-[5-(2,4-dimethyl-1,3-thiazol-5-yl)-1,2,4-oxadiazol-3-yl]phenyl}-4-methylbenzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L294-0459
N-{4-[5-(2,4-dimethyl-1,3-thiazol-5-yl)-1,2,4-oxadiazol-3-yl]phenyl}-4-methylbenzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L294-0459

Molecular Formula

C20H18N4O3S2 (C20 H18 N4 O3 S2)

Compound Name

N-{4-[5-(2,4-dimethyl-1,3-thiazol-5-yl)-1,2,4-oxadiazol-3-yl]phenyl}-4-methylbenzene-1-sulfonamide

IUPAC name

N-{4-[5-(24-dimethyl-13-thiazol-5-yl)-124-oxadiazol-3-yl]phenyl}-4-methylbenzene-1-sulfonamide

SMILES

Cc1c(-c2nc(-c(cc3)ccc3NS(c3ccc(C)cc3)(=O)=O)no2)sc(C)n1

InChI

InChI=1S/C20H18N4O3S2/c1-12-4-10-17(11-5-12)29(25,26)24-16-8-6-15(7-9-16)19-22-20(27-23-19)18-13(2)21-14(3)28-18/h4-11,24H,1-3H3

InChI Key

MVPASSQCVPUMDR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27241820

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

426.52

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.061

Distribution Coefficient, logD

5.054

Water Solubility, LogSw

-4.66

Polar Surface Area

82.683

Acid Dissociation Constant (pKa)

9.18

Base Dissociation Constant (pKb)

3.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.00

L294-0459 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L294-0459 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L294-0459?
Check Price and Availability of L294-0459, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L294-0459 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L294-0459
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L294-0459
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L294-0459 available by request