L294-0884 Screening compound: N-(4-{5-[(1E)-2-(2-methoxyphenyl)ethenyl]-1,2,4-oxadiazol-3-yl}phenyl)thiophene-2-sulfonamide

L294-0884 Screening compound: N-(4-{5-[(1E)-2-(2-methoxyphenyl)ethenyl]-1,2,4-oxadiazol-3-yl}phenyl)thiophene-2-sulfonamide
L294-0884 Screening compound: N-(4-{5-[(1E)-2-(2-methoxyphenyl)ethenyl]-1,2,4-oxadiazol-3-yl}phenyl)thiophene-2-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L294-0884
N-(4-{5-[(1E)-2-(2-methoxyphenyl)ethenyl]-1,2,4-oxadiazol-3-yl}phenyl)thiophene-2-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L294-0884

Molecular Formula

C21H17N3O4S2 (C21 H17 N3 O4 S2)

Compound Name

N-(4-{5-[(1E)-2-(2-methoxyphenyl)ethenyl]-1,2,4-oxadiazol-3-yl}phenyl)thiophene-2-sulfonamide

IUPAC name

N-(4-{5-[(1E)-2-(2-methoxyphenyl)ethenyl]-124-oxadiazol-3-yl}phenyl)thiophene-2-sulfonamide

SMILES

COc1c(/C=C/c2nc(-c(cc3)ccc3NS(c3cccs3)(=O)=O)no2)cccc1

InChI

InChI=1S/C21H17N3O4S2/c1-27-18-6-3-2-5-15(18)10-13-19-22-21(23-28-19)16-8-11-17(12-9-16)24-30(25,26)20-7-4-14-29-20/h2-14,24H,1H3

InChI Key

NLMXRHDZQIXNSI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27241885

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

439.52

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.607

Distribution Coefficient, logD

5.606

Water Solubility, LogSw

-5.75

Polar Surface Area

80.608

Acid Dissociation Constant (pKa)

9.98

Base Dissociation Constant (pKb)

-7.03

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.80

L294-0884 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

KRAS-Targeted Library (16000 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L294-0884 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L294-0884?
Check Price and Availability of L294-0884, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L294-0884 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L294-0884
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L294-0884
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L294-0884 available by request