L295-0479 Screening compound: 2-{[3,5,6-trimethyl-2-(piperidine-1-carbonyl)-1-benzofuran-7-yl]sulfonyl}-1,2,3,4-tetrahydroisoquinoline

L295-0479 Screening compound: 2-{[3,5,6-trimethyl-2-(piperidine-1-carbonyl)-1-benzofuran-7-yl]sulfonyl}-1,2,3,4-tetrahydroisoquinoline
L295-0479 Screening compound: 2-{[3,5,6-trimethyl-2-(piperidine-1-carbonyl)-1-benzofuran-7-yl]sulfonyl}-1,2,3,4-tetrahydroisoquinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound L295-0479
2-{[3,5,6-trimethyl-2-(piperidine-1-carbonyl)-1-benzofuran-7-yl]sulfonyl}-1,2,3,4-tetrahydroisoquinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L295-0479

Molecular Formula

C26H30N2O4S (C26 H30 N2 O4 S)

Compound Name

2-{[3,5,6-trimethyl-2-(piperidine-1-carbonyl)-1-benzofuran-7-yl]sulfonyl}-1,2,3,4-tetrahydroisoquinoline

IUPAC name

2-{[356-trimethyl-2-(piperidine-1-carbonyl)-1-benzofuran-7-yl]sulfonyl}-1234-tetrahydroisoquinoline

SMILES

Cc1c(C(N2CCCCC2)=O)oc2c1cc(C)c(C)c2S(N(CC1)Cc2c1cccc2)(=O)=O

InChI

InChI=1S/C26H30N2O4S/c1-17-15-22-19(3)23(26(29)27-12-7-4-8-13-27)32-24(22)25(18(17)2)33(30,31)28-14-11-20-9-5-6-10-21(20)16-28/h5-6,9-10,15H,4,7-8,11-14,16H2,1-3H3

InChI Key

LTCKBMGVJRLEHI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27242045

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

466.6

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.114

Distribution Coefficient, logD

5.114

Water Solubility, LogSw

-4.97

Polar Surface Area

57.018

Acid Dissociation Constant (pKa)

25.79

Base Dissociation Constant (pKb)

0.45

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.30

L295-0479 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L295-0479 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L295-0479?
Check Price and Availability of L295-0479, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L295-0479 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L295-0479
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L295-0479
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L295-0479 available by request