L295-0495 Screening compound: 3,5,6-trimethyl-N-(4-methylpyridin-2-yl)-2-(piperidine-1-carbonyl)-1-benzofuran-7-sulfonamide

L295-0495 Screening compound: 3,5,6-trimethyl-N-(4-methylpyridin-2-yl)-2-(piperidine-1-carbonyl)-1-benzofuran-7-sulfonamide
L295-0495 Screening compound: 3,5,6-trimethyl-N-(4-methylpyridin-2-yl)-2-(piperidine-1-carbonyl)-1-benzofuran-7-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L295-0495
3,5,6-trimethyl-N-(4-methylpyridin-2-yl)-2-(piperidine-1-carbonyl)-1-benzofuran-7-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L295-0495

Molecular Formula

C23H27N3O4S (C23 H27 N3 O4 S)

Compound Name

3,5,6-trimethyl-N-(4-methylpyridin-2-yl)-2-(piperidine-1-carbonyl)-1-benzofuran-7-sulfonamide

IUPAC name

356-trimethyl-N-(4-methylpyridin-2-yl)-2-(piperidine-1-carbonyl)-1-benzofuran-7-sulfonamide

SMILES

Cc1c(C(N2CCCCC2)=O)oc2c1cc(C)c(C)c2S(Nc1nccc(C)c1)(=O)=O

InChI

InChI=1S/C23H27N3O4S/c1-14-8-9-24-19(12-14)25-31(28,29)22-16(3)15(2)13-18-17(4)20(30-21(18)22)23(27)26-10-6-5-7-11-26/h8-9,12-13H,5-7,10-11H2,1-4H3,(H,24,25)

InChI Key

XWTZQXSPIOFQLY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27242055

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

441.55

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.225

Distribution Coefficient, logD

2.299

Water Solubility, LogSw

-4.02

Polar Surface Area

75.910

Acid Dissociation Constant (pKa)

5.48

Base Dissociation Constant (pKb)

2.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.10

L295-0495 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with L295-0495 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L295-0495?
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What is the minimum amount of L295-0495 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L295-0495
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L295-0495
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L295-0495 available by request