L295-1359 Screening compound: 2-methyl-1-{[3,5,6-trimethyl-2-(morpholine-4-carbonyl)-1-benzofuran-7-yl]sulfonyl}-2,3-dihydro-1H-indole

L295-1359 Screening compound: 2-methyl-1-{[3,5,6-trimethyl-2-(morpholine-4-carbonyl)-1-benzofuran-7-yl]sulfonyl}-2,3-dihydro-1H-indole
L295-1359 Screening compound: 2-methyl-1-{[3,5,6-trimethyl-2-(morpholine-4-carbonyl)-1-benzofuran-7-yl]sulfonyl}-2,3-dihydro-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound L295-1359
2-methyl-1-{[3,5,6-trimethyl-2-(morpholine-4-carbonyl)-1-benzofuran-7-yl]sulfonyl}-2,3-dihydro-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L295-1359

Molecular Formula

C25H28N2O5S (C25 H28 N2 O5 S)

Compound Name

2-methyl-1-{[3,5,6-trimethyl-2-(morpholine-4-carbonyl)-1-benzofuran-7-yl]sulfonyl}-2,3-dihydro-1H-indole

IUPAC name

2-methyl-1-{[356-trimethyl-2-(morpholine-4-carbonyl)-1-benzofuran-7-yl]sulfonyl}-23-dihydro-1H-indole

SMILES

CC(Cc1c2cccc1)N2S(c1c(C)c(C)cc2c1oc(C(N1CCOCC1)=O)c2C)(=O)=O

InChI

InChI=1S/C25H28N2O5S/c1-15-13-20-18(4)22(25(28)26-9-11-31-12-10-26)32-23(20)24(17(15)3)33(29,30)27-16(2)14-19-7-5-6-8-21(19)27/h5-8,13,16H,9-12,14H2,1-4H3/t16-/m0/s1

InChI Key

UGDYPGXUFNMLLB-INIZCTEOSA-N

MDL Number (MFCD)

MFCD27242192

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

468.57

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.246

Distribution Coefficient, logD

4.246

Water Solubility, LogSw

-4.22

Polar Surface Area

64.788

Acid Dissociation Constant (pKa)

26.07

Base Dissociation Constant (pKb)

-1.40

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

40.00

L295-1359 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Neuropeptide S Library (2850 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Nervous system
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L295-1359 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L295-1359?
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What is the minimum amount of L295-1359 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L295-1359
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L295-1359
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L295-1359 available by request