L299-0428 Screening compound: N-(4-chloro-2-methylphenyl)-2-methyl-5-{2-methyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}benzene-1-sulfonamide

L299-0428 Screening compound: N-(4-chloro-2-methylphenyl)-2-methyl-5-{2-methyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}benzene-1-sulfonamide
L299-0428 Screening compound: N-(4-chloro-2-methylphenyl)-2-methyl-5-{2-methyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L299-0428
N-(4-chloro-2-methylphenyl)-2-methyl-5-{2-methyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L299-0428

Molecular Formula

C22H21ClN4O4S (C22 H21 ClN4 O4 S)

Compound Name

N-(4-chloro-2-methylphenyl)-2-methyl-5-{2-methyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}benzene-1-sulfonamide

IUPAC name

N-(4-chloro-2-methylphenyl)-2-methyl-5-{2-methyl-58-dioxo-4H5H6H7H8H-pyrazolo[15-a][13]diazepin-3-yl}benzene-1-sulfonamide

SMILES

Cc(c(-c1cc(S(Nc(cc2)c(C)cc2Cl)(=O)=O)c(C)cc1)c1NC(CC2)=O)nn1C2=O

InChI

InChI=1S/C22H21ClN4O4S/c1-12-4-5-15(21-14(3)25-27-20(29)9-8-19(28)24-22(21)27)11-18(12)32(30,31)26-17-7-6-16(23)10-13(17)2/h4-7,10-11,26H,8-9H2,1-3H3,(H,24,28)

InChI Key

PMQICFZMJLHKQN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15123227

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

472.95

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.037

Distribution Coefficient, logD

1.091

Water Solubility, LogSw

-3.98

Polar Surface Area

92.365

Acid Dissociation Constant (pKa)

5.46

Base Dissociation Constant (pKb)

-2.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

L299-0428 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L299-0428 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L299-0428?
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What is the minimum amount of L299-0428 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L299-0428
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L299-0428
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L299-0428 available by request