L299-0554 Screening compound: N-(3-chloro-4-methoxyphenyl)-2-methyl-5-{2-methyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}benzene-1-sulfonamide

L299-0554 Screening compound: N-(3-chloro-4-methoxyphenyl)-2-methyl-5-{2-methyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}benzene-1-sulfonamide
L299-0554 Screening compound: N-(3-chloro-4-methoxyphenyl)-2-methyl-5-{2-methyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L299-0554
N-(3-chloro-4-methoxyphenyl)-2-methyl-5-{2-methyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L299-0554

Molecular Formula

C22H21ClN4O5S (C22 H21 ClN4 O5 S)

Compound Name

N-(3-chloro-4-methoxyphenyl)-2-methyl-5-{2-methyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}benzene-1-sulfonamide

IUPAC name

N-(3-chloro-4-methoxyphenyl)-2-methyl-5-{2-methyl-58-dioxo-4H5H6H7H8H-pyrazolo[15-a][13]diazepin-3-yl}benzene-1-sulfonamide

SMILES

Cc(c(-c1cc(S(Nc(cc2)cc(Cl)c2OC)(=O)=O)c(C)cc1)c1NC(CC2)=O)nn1C2=O

InChI

InChI=1S/C22H21ClN4O5S/c1-12-4-5-14(21-13(2)25-27-20(29)9-8-19(28)24-22(21)27)10-18(12)33(30,31)26-15-6-7-17(32-3)16(23)11-15/h4-7,10-11,26H,8-9H2,1-3H3,(H,24,28)

InChI Key

HAPIXTIMXKLXGP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15123280

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

488.95

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.442

Distribution Coefficient, logD

0.330

Water Solubility, LogSw

-3.72

Polar Surface Area

100.693

Acid Dissociation Constant (pKa)

5.29

Base Dissociation Constant (pKb)

-2.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

L299-0554 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L299-0554 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L299-0554?
Check Price and Availability of L299-0554, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L299-0554 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L299-0554
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L299-0554
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L299-0554 available by request