L299-0612 Screening compound: methyl 4-(2-methyl-5-{2-methyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}benzenesulfonamido)benzoate

L299-0612 Screening compound: methyl 4-(2-methyl-5-{2-methyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}benzenesulfonamido)benzoate
L299-0612 Screening compound: methyl 4-(2-methyl-5-{2-methyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}benzenesulfonamido)benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound L299-0612
methyl 4-(2-methyl-5-{2-methyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}benzenesulfonamido)benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L299-0612

Molecular Formula

C23H22N4O6S (C23 H22 N4 O6 S)

Compound Name

methyl 4-(2-methyl-5-{2-methyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}benzenesulfonamido)benzoate

IUPAC name

methyl 4-(2-methyl-5-{2-methyl-58-dioxo-4H5H6H7H8H-pyrazolo[15-a][13]diazepin-3-yl}benzenesulfonamido)benzoate

SMILES

Cc(c(-c1cc(S(Nc(cc2)ccc2C(OC)=O)(=O)=O)c(C)cc1)c1NC(CC2)=O)nn1C2=O

InChI

InChI=1S/C23H22N4O6S/c1-13-4-5-16(21-14(2)25-27-20(29)11-10-19(28)24-22(21)27)12-18(13)34(31,32)26-17-8-6-15(7-9-17)23(30)33-3/h4-9,12,26H,10-11H2,1-3H3,(H,24,28)

InChI Key

SHCLWHDVEHQXIJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27242340

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

482.52

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.055

Distribution Coefficient, logD

0.450

Water Solubility, LogSw

-2.89

Polar Surface Area

114.237

Acid Dissociation Constant (pKa)

5.81

Base Dissociation Constant (pKb)

-2.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.70

L299-0612 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Mechanism of action:
  • PPI modulators
  • PPI modulators
Targets:
  • Phosphatases
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L299-0612 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L299-0612?
Check Price and Availability of L299-0612, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L299-0612 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L299-0612
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L299-0612
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L299-0612 available by request