L299-0884 Screening compound: 2-chloro-5-{2-methyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}-N-propylbenzene-1-sulfonamide

L299-0884 Screening compound: 2-chloro-5-{2-methyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}-N-propylbenzene-1-sulfonamide
L299-0884 Screening compound: 2-chloro-5-{2-methyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}-N-propylbenzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L299-0884
2-chloro-5-{2-methyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}-N-propylbenzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L299-0884

Molecular Formula

C17H19ClN4O4S (C17 H19 ClN4 O4 S)

Compound Name

2-chloro-5-{2-methyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}-N-propylbenzene-1-sulfonamide

IUPAC name

2-chloro-5-{2-methyl-58-dioxo-4H5H6H7H8H-pyrazolo[15-a][13]diazepin-3-yl}-N-propylbenzene-1-sulfonamide

SMILES

CCCNS(c(cc(cc1)-c2c(NC(CCC3=O)=O)n3nc2C)c1Cl)(=O)=O

InChI

InChI=1S/C17H19ClN4O4S/c1-3-8-19-27(25,26)13-9-11(4-5-12(13)18)16-10(2)21-22-15(24)7-6-14(23)20-17(16)22/h4-5,9,19H,3,6-8H2,1-2H3,(H,20,23)

InChI Key

DKYWHOHIXREWPL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27242361

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

410.88

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.250

Distribution Coefficient, logD

0.964

Water Solubility, LogSw

-3.20

Polar Surface Area

94.285

Acid Dissociation Constant (pKa)

7.43

Base Dissociation Constant (pKb)

-2.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.30

L299-0884 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Immunological Library (6760 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Immune system
Targets:
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L299-0884 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L299-0884?
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What is the minimum amount of L299-0884 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L299-0884
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L299-0884
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L299-0884 available by request