L299-0909 Screening compound: N-(3-acetylphenyl)-2-chloro-5-{2-methyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}benzene-1-sulfonamide

L299-0909 Screening compound: N-(3-acetylphenyl)-2-chloro-5-{2-methyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}benzene-1-sulfonamide
L299-0909 Screening compound: N-(3-acetylphenyl)-2-chloro-5-{2-methyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L299-0909
N-(3-acetylphenyl)-2-chloro-5-{2-methyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L299-0909

Molecular Formula

C22H19ClN4O5S (C22 H19 ClN4 O5 S)

Compound Name

N-(3-acetylphenyl)-2-chloro-5-{2-methyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}benzene-1-sulfonamide

IUPAC name

N-(3-acetylphenyl)-2-chloro-5-{2-methyl-58-dioxo-4H5H6H7H8H-pyrazolo[15-a][13]diazepin-3-yl}benzene-1-sulfonamide

SMILES

CC(c1cccc(NS(c(cc(cc2)-c3c(NC(CCC4=O)=O)n4nc3C)c2Cl)(=O)=O)c1)=O

InChI

InChI=1S/C22H19ClN4O5S/c1-12-21(22-24-19(29)8-9-20(30)27(22)25-12)15-6-7-17(23)18(11-15)33(31,32)26-16-5-3-4-14(10-16)13(2)28/h3-7,10-11,26H,8-9H2,1-2H3,(H,24,29)

InChI Key

OAECGCSFXGCRKY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27242367

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

486.94

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.607

Distribution Coefficient, logD

0.636

Water Solubility, LogSw

-3.24

Polar Surface Area

106.889

Acid Dissociation Constant (pKa)

6.48

Base Dissociation Constant (pKb)

-2.44

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

L299-0909 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Allosteric Kinases Inhibitors Library (23117 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L299-0909 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L299-0909?
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What is the minimum amount of L299-0909 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L299-0909
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L299-0909
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L299-0909 available by request