L299-3783 Screening compound: 5-{2-ethyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}-2-methoxy-N-[(2-methylphenyl)methyl]benzene-1-sulfonamide

L299-3783 Screening compound: 5-{2-ethyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}-2-methoxy-N-[(2-methylphenyl)methyl]benzene-1-sulfonamide
L299-3783 Screening compound: 5-{2-ethyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}-2-methoxy-N-[(2-methylphenyl)methyl]benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L299-3783
5-{2-ethyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}-2-methoxy-N-[(2-methylphenyl)methyl]benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L299-3783

Molecular Formula

C24H26N4O5S (C24 H26 N4 O5 S)

Compound Name

5-{2-ethyl-5,8-dioxo-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}-2-methoxy-N-[(2-methylphenyl)methyl]benzene-1-sulfonamide

IUPAC name

5-{2-ethyl-58-dioxo-4H5H6H7H8H-pyrazolo[15-a][13]diazepin-3-yl}-2-methoxy-N-[(2-methylphenyl)methyl]benzene-1-sulfonamide

SMILES

CCc(c(-c(cc1)cc(S(NCc2c(C)cccc2)(=O)=O)c1OC)c1NC(CC2)=O)nn1C2=O

InChI

InChI=1S/C24H26N4O5S/c1-4-18-23(24-26-21(29)11-12-22(30)28(24)27-18)16-9-10-19(33-3)20(13-16)34(31,32)25-14-17-8-6-5-7-15(17)2/h5-10,13,25H,4,11-12,14H2,1-3H3,(H,26,29)

InChI Key

FYIRHRHBKQXRBF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27242563

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

482.56

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.867

Distribution Coefficient, logD

2.592

Water Solubility, LogSw

-3.43

Polar Surface Area

102.491

Acid Dissociation Constant (pKa)

7.45

Base Dissociation Constant (pKb)

-2.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

L299-3783 in Drug Discovery

Included in Screening Libraries

Nucleic Acid Ligands (8311 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L299-3783 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L299-3783?
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What is the minimum amount of L299-3783 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L299-3783
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L299-3783
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L299-3783 available by request