L299-6179 Screening compound: N-(3,4-dimethylphenyl)-5-{5,8-dioxo-2-propyl-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}-2-methoxybenzene-1-sulfonamide

L299-6179 Screening compound: N-(3,4-dimethylphenyl)-5-{5,8-dioxo-2-propyl-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}-2-methoxybenzene-1-sulfonamide
L299-6179 Screening compound: N-(3,4-dimethylphenyl)-5-{5,8-dioxo-2-propyl-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}-2-methoxybenzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L299-6179
N-(3,4-dimethylphenyl)-5-{5,8-dioxo-2-propyl-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}-2-methoxybenzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L299-6179

Molecular Formula

C25H28N4O5S (C25 H28 N4 O5 S)

Compound Name

N-(3,4-dimethylphenyl)-5-{5,8-dioxo-2-propyl-4H,5H,6H,7H,8H-pyrazolo[1,5-a][1,3]diazepin-3-yl}-2-methoxybenzene-1-sulfonamide

IUPAC name

N-(34-dimethylphenyl)-5-{58-dioxo-2-propyl-4H5H6H7H8H-pyrazolo[15-a][13]diazepin-3-yl}-2-methoxybenzene-1-sulfonamide

SMILES

CCCc(c(-c(cc1)cc(S(Nc2cc(C)c(C)cc2)(=O)=O)c1OC)c1NC(CC2)=O)nn1C2=O

InChI

InChI=1S/C25H28N4O5S/c1-5-6-19-24(25-26-22(30)11-12-23(31)29(25)27-19)17-8-10-20(34-4)21(14-17)35(32,33)28-18-9-7-15(2)16(3)13-18/h7-10,13-14,28H,5-6,11-12H2,1-4H3,(H,26,30)

InChI Key

FVGOIUILRKVMJU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27242641

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

496.59

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.617

Distribution Coefficient, logD

3.342

Water Solubility, LogSw

-4.03

Polar Surface Area

101.382

Acid Dissociation Constant (pKa)

7.45

Base Dissociation Constant (pKb)

-2.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

L299-6179 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Recognition Elements PPI Library (24135 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L299-6179 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L299-6179?
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What is the minimum amount of L299-6179 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L299-6179
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L299-6179
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L299-6179 available by request