L302-0128 Screening compound: 1-acetyl-N-(4-cyanophenyl)-3,3-dimethyl-2,3-dihydro-1H-indole-5-sulfonamide

L302-0128 Screening compound: 1-acetyl-N-(4-cyanophenyl)-3,3-dimethyl-2,3-dihydro-1H-indole-5-sulfonamide
L302-0128 Screening compound: 1-acetyl-N-(4-cyanophenyl)-3,3-dimethyl-2,3-dihydro-1H-indole-5-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L302-0128
1-acetyl-N-(4-cyanophenyl)-3,3-dimethyl-2,3-dihydro-1H-indole-5-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L302-0128

Molecular Formula

C19H19N3O3S (C19 H19 N3 O3 S)

Compound Name

1-acetyl-N-(4-cyanophenyl)-3,3-dimethyl-2,3-dihydro-1H-indole-5-sulfonamide

IUPAC name

1-acetyl-N-(4-cyanophenyl)-33-dimethyl-23-dihydro-1H-indole-5-sulfonamide

SMILES

CC(C)(C1)c(cc(cc2)S(Nc(cc3)ccc3C#N)(=O)=O)c2N1C(C)=O

InChI

InChI=1S/C19H19N3O3S/c1-13(23)22-12-19(2,3)17-10-16(8-9-18(17)22)26(24,25)21-15-6-4-14(11-20)5-7-15/h4-10,21H,12H2,1-3H3

InChI Key

UNHZOAKVLLDKSR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27242717

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

369.44

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.963

Distribution Coefficient, logD

2.681

Water Solubility, LogSw

-3.64

Polar Surface Area

74.296

Acid Dissociation Constant (pKa)

7.44

Base Dissociation Constant (pKb)

-3.67

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.30

L302-0128 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

RAR (Nuclear receptors) Ligands Library (6524 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Respiratory tract
  • Eye
  • Male
  • Female
  • Hemic and lymphatic
  • Congenital
  • Skin
  • Endocrine
  • Immune system
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L302-0128 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L302-0128?
Check Price and Availability of L302-0128, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L302-0128 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L302-0128
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L302-0128
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L302-0128 available by request