L302-1344 Screening compound: 1-cyclopropanecarbonyl-5-{[4-(furan-2-carbonyl)piperazin-1-yl]sulfonyl}-3,3-dimethyl-2,3-dihydro-1H-indole

L302-1344 Screening compound: 1-cyclopropanecarbonyl-5-{[4-(furan-2-carbonyl)piperazin-1-yl]sulfonyl}-3,3-dimethyl-2,3-dihydro-1H-indole
L302-1344 Screening compound: 1-cyclopropanecarbonyl-5-{[4-(furan-2-carbonyl)piperazin-1-yl]sulfonyl}-3,3-dimethyl-2,3-dihydro-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound L302-1344
1-cyclopropanecarbonyl-5-{[4-(furan-2-carbonyl)piperazin-1-yl]sulfonyl}-3,3-dimethyl-2,3-dihydro-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L302-1344

Molecular Formula

C23H27N3O5S (C23 H27 N3 O5 S)

Compound Name

1-cyclopropanecarbonyl-5-{[4-(furan-2-carbonyl)piperazin-1-yl]sulfonyl}-3,3-dimethyl-2,3-dihydro-1H-indole

IUPAC name

1-cyclopropanecarbonyl-5-{[4-(furan-2-carbonyl)piperazin-1-yl]sulfonyl}-33-dimethyl-23-dihydro-1H-indole

SMILES

CC(C)(C1)c(cc(cc2)S(N(CC3)CCN3C(c3ccco3)=O)(=O)=O)c2N1C(C1CC1)=O

InChI

InChI=1S/C23H27N3O5S/c1-23(2)15-26(21(27)16-5-6-16)19-8-7-17(14-18(19)23)32(29,30)25-11-9-24(10-12-25)22(28)20-4-3-13-31-20/h3-4,7-8,13-14,16H,5-6,9-12,15H2,1-2H3

InChI Key

BJWIJPKTVOSDPY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27242976

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

457.55

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.831

Distribution Coefficient, logD

2.831

Water Solubility, LogSw

-3.51

Polar Surface Area

73.119

Acid Dissociation Constant (pKa)

21.07

Base Dissociation Constant (pKb)

-2.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.80

L302-1344 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L302-1344 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L302-1344?
Check Price and Availability of L302-1344, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L302-1344 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L302-1344
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L302-1344
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L302-1344 available by request