L303-0974 Screening compound: 1-[4-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)benzenesulfonyl]-N-[2-(morpholin-4-yl)ethyl]piperidine-4-carboxamide

L303-0974 Screening compound: 1-[4-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)benzenesulfonyl]-N-[2-(morpholin-4-yl)ethyl]piperidine-4-carboxamide
L303-0974 Screening compound: 1-[4-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)benzenesulfonyl]-N-[2-(morpholin-4-yl)ethyl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L303-0974
1-[4-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)benzenesulfonyl]-N-[2-(morpholin-4-yl)ethyl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L303-0974

Molecular Formula

C23H31N5O5S (C23 H31 N5 O5 S)

Compound Name

1-[4-(5-cyclopropyl-1,2,4-oxadiazol-3-yl)benzenesulfonyl]-N-[2-(morpholin-4-yl)ethyl]piperidine-4-carboxamide

IUPAC name

1-[4-(5-cyclopropyl-124-oxadiazol-3-yl)benzenesulfonyl]-N-[2-(morpholin-4-yl)ethyl]piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1S(c(cc1)ccc1-c1noc(C2CC2)n1)(=O)=O)NCCN1CCOCC1

InChI

InChI=1S/C23H31N5O5S/c29-22(24-9-12-27-13-15-32-16-14-27)18-7-10-28(11-8-18)34(30,31)20-5-3-17(4-6-20)21-25-23(33-26-21)19-1-2-19/h3-6,18-19H,1-2,7-16H2,(H,24,29)

InChI Key

QPDGMANVYSEFMT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27243046

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

489.6

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.191

Distribution Coefficient, logD

2.100

Water Solubility, LogSw

-2.71

Polar Surface Area

100.024

Acid Dissociation Constant (pKa)

13.35

Base Dissociation Constant (pKb)

6.77

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

60.90

L303-0974 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L303-0974 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L303-0974?
Check Price and Availability of L303-0974, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L303-0974 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L303-0974
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L303-0974
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L303-0974 available by request