L303-2385 Screening compound: 2-[3-(4-{[4-(pyrrolidine-1-carbonyl)piperidin-1-yl]sulfonyl}phenyl)-1,2,4-oxadiazol-5-yl]pyridine

L303-2385 Screening compound: 2-[3-(4-{[4-(pyrrolidine-1-carbonyl)piperidin-1-yl]sulfonyl}phenyl)-1,2,4-oxadiazol-5-yl]pyridine
L303-2385 Screening compound: 2-[3-(4-{[4-(pyrrolidine-1-carbonyl)piperidin-1-yl]sulfonyl}phenyl)-1,2,4-oxadiazol-5-yl]pyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound L303-2385
2-[3-(4-{[4-(pyrrolidine-1-carbonyl)piperidin-1-yl]sulfonyl}phenyl)-1,2,4-oxadiazol-5-yl]pyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L303-2385

Molecular Formula

C23H25N5O4S (C23 H25 N5 O4 S)

Compound Name

2-[3-(4-{[4-(pyrrolidine-1-carbonyl)piperidin-1-yl]sulfonyl}phenyl)-1,2,4-oxadiazol-5-yl]pyridine

IUPAC name

2-[3-(4-{[4-(pyrrolidine-1-carbonyl)piperidin-1-yl]sulfonyl}phenyl)-124-oxadiazol-5-yl]pyridine

SMILES

O=C(C(CC1)CCN1S(c(cc1)ccc1-c1noc(-c2ncccc2)n1)(=O)=O)N1CCCC1

InChI

InChI=1S/C23H25N5O4S/c29-23(27-13-3-4-14-27)18-10-15-28(16-11-18)33(30,31)19-8-6-17(7-9-19)21-25-22(32-26-21)20-5-1-2-12-24-20/h1-2,5-9,12,18H,3-4,10-11,13-16H2

InChI Key

ORPSWUNIXRZXSD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27243074

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

467.55

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.017

Distribution Coefficient, logD

3.017

Water Solubility, LogSw

-3.23

Polar Surface Area

89.417

Acid Dissociation Constant (pKa)

23.63

Base Dissociation Constant (pKb)

1.41

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.10

L303-2385 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L303-2385 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L303-2385?
Check Price and Availability of L303-2385, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L303-2385 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L303-2385
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L303-2385
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L303-2385 available by request