L303-2466 Screening compound: 1-{4-[5-(3-fluoro-4-methylphenyl)-1,2,4-oxadiazol-3-yl]benzenesulfonyl}-4-(pyrrolidine-1-carbonyl)piperidine

L303-2466 Screening compound: 1-{4-[5-(3-fluoro-4-methylphenyl)-1,2,4-oxadiazol-3-yl]benzenesulfonyl}-4-(pyrrolidine-1-carbonyl)piperidine
L303-2466 Screening compound: 1-{4-[5-(3-fluoro-4-methylphenyl)-1,2,4-oxadiazol-3-yl]benzenesulfonyl}-4-(pyrrolidine-1-carbonyl)piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound L303-2466
1-{4-[5-(3-fluoro-4-methylphenyl)-1,2,4-oxadiazol-3-yl]benzenesulfonyl}-4-(pyrrolidine-1-carbonyl)piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L303-2466

Molecular Formula

C25H27FN4O4S (C25 H27 FN4 O4 S)

Compound Name

1-{4-[5-(3-fluoro-4-methylphenyl)-1,2,4-oxadiazol-3-yl]benzenesulfonyl}-4-(pyrrolidine-1-carbonyl)piperidine

IUPAC name

1-{4-[5-(3-fluoro-4-methylphenyl)-124-oxadiazol-3-yl]benzenesulfonyl}-4-(pyrrolidine-1-carbonyl)piperidine

SMILES

Cc(ccc(-c1nc(-c(cc2)ccc2S(N(CC2)CCC2C(N2CCCC2)=O)(=O)=O)no1)c1)c1F

InChI

InChI=1S/C25H27FN4O4S/c1-17-4-5-20(16-22(17)26)24-27-23(28-34-24)18-6-8-21(9-7-18)35(32,33)30-14-10-19(11-15-30)25(31)29-12-2-3-13-29/h4-9,16,19H,2-3,10-15H2,1H3

InChI Key

NDXLJFCHDGJVQE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27243087

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

498.58

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.744

Distribution Coefficient, logD

4.744

Water Solubility, LogSw

-4.59

Polar Surface Area

80.369

Acid Dissociation Constant (pKa)

23.63

Base Dissociation Constant (pKb)

-1.28

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

L303-2466 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular

References: we are preparing a list of scientific research reports with L303-2466 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L303-2466?
Check Price and Availability of L303-2466, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L303-2466 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L303-2466
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L303-2466
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L303-2466 available by request