L303-3267 Screening compound: 1-(4-{5-[(1E)-2-(2-methoxyphenyl)ethenyl]-1,2,4-oxadiazol-3-yl}benzenesulfonyl)-4-(pyrrolidine-1-carbonyl)piperidine

L303-3267 Screening compound: 1-(4-{5-[(1E)-2-(2-methoxyphenyl)ethenyl]-1,2,4-oxadiazol-3-yl}benzenesulfonyl)-4-(pyrrolidine-1-carbonyl)piperidine
L303-3267 Screening compound: 1-(4-{5-[(1E)-2-(2-methoxyphenyl)ethenyl]-1,2,4-oxadiazol-3-yl}benzenesulfonyl)-4-(pyrrolidine-1-carbonyl)piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound L303-3267
1-(4-{5-[(1E)-2-(2-methoxyphenyl)ethenyl]-1,2,4-oxadiazol-3-yl}benzenesulfonyl)-4-(pyrrolidine-1-carbonyl)piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L303-3267

Molecular Formula

C27H30N4O5S (C27 H30 N4 O5 S)

Compound Name

1-(4-{5-[(1E)-2-(2-methoxyphenyl)ethenyl]-1,2,4-oxadiazol-3-yl}benzenesulfonyl)-4-(pyrrolidine-1-carbonyl)piperidine

IUPAC name

1-(4-{5-[(1E)-2-(2-methoxyphenyl)ethenyl]-124-oxadiazol-3-yl}benzenesulfonyl)-4-(pyrrolidine-1-carbonyl)piperidine

SMILES

COc1c(/C=C/c2nc(-c(cc3)ccc3S(N(CC3)CCC3C(N3CCCC3)=O)(=O)=O)no2)cccc1

InChI

InChI=1S/C27H30N4O5S/c1-35-24-7-3-2-6-20(24)10-13-25-28-26(29-36-25)21-8-11-23(12-9-21)37(33,34)31-18-14-22(15-19-31)27(32)30-16-4-5-17-30/h2-3,6-13,22H,4-5,14-19H2,1H3

InChI Key

IZAJLKCQWJOWNB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27243097

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

522.63

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

5.011

Distribution Coefficient, logD

5.011

Water Solubility, LogSw

-4.68

Polar Surface Area

87.666

Acid Dissociation Constant (pKa)

23.63

Base Dissociation Constant (pKb)

-1.28

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.00

L303-3267 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L303-3267 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L303-3267?
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What is the minimum amount of L303-3267 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L303-3267
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L303-3267
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L303-3267 available by request