L304-0890 Screening compound: N-(2-bromo-4-methylphenyl)-3-(4-methoxyphenyl)-7-methyl-5-oxo-4H,5H-pyrazolo[1,5-a]pyrimidine-2-carboxamide

L304-0890 Screening compound: N-(2-bromo-4-methylphenyl)-3-(4-methoxyphenyl)-7-methyl-5-oxo-4H,5H-pyrazolo[1,5-a]pyrimidine-2-carboxamide
L304-0890 Screening compound: N-(2-bromo-4-methylphenyl)-3-(4-methoxyphenyl)-7-methyl-5-oxo-4H,5H-pyrazolo[1,5-a]pyrimidine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L304-0890
N-(2-bromo-4-methylphenyl)-3-(4-methoxyphenyl)-7-methyl-5-oxo-4H,5H-pyrazolo[1,5-a]pyrimidine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L304-0890

Molecular Formula

C22H19BrN4O3 (C22 H19 BrN4 O3)

Compound Name

N-(2-bromo-4-methylphenyl)-3-(4-methoxyphenyl)-7-methyl-5-oxo-4H,5H-pyrazolo[1,5-a]pyrimidine-2-carboxamide

IUPAC name

N-(2-bromo-4-methylphenyl)-3-(4-methoxyphenyl)-7-methyl-5-oxo-4H5H-pyrazolo[15-a]pyrimidine-2-carboxamide

SMILES

Cc(cc1)cc(Br)c1NC(c(c(-c(cc1)ccc1OC)c1N2)nn1C(C)=CC2=O)=O

InChI

InChI=1S/C22H19BrN4O3/c1-12-4-9-17(16(23)10-12)24-22(29)20-19(14-5-7-15(30-3)8-6-14)21-25-18(28)11-13(2)27(21)26-20/h4-11H,1-3H3,(H,24,29)(H,25,28)

InChI Key

WXGIUYPULCQORW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15123388

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

467.32

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.354

Distribution Coefficient, logD

4.337

Water Solubility, LogSw

-4.51

Polar Surface Area

67.965

Acid Dissociation Constant (pKa)

8.78

Base Dissociation Constant (pKb)

-3.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

L304-0890 in Drug Discovery

Included in Screening Libraries

BRD4 Targeted Library (4534 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Hemic and lymphatic
  • Cardiovascular
  • Metabolic
Targets:
  • Others

References: we are preparing a list of scientific research reports with L304-0890 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L304-0890?
Check Price and Availability of L304-0890, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L304-0890 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L304-0890
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L304-0890
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L304-0890 available by request