L306-1265 Screening compound: 3-(propan-2-yl)-6-{[4-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidin-1-yl]sulfonyl}-2,3-dihydro-1,3-benzothiazol-2-one

L306-1265 Screening compound: 3-(propan-2-yl)-6-{[4-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidin-1-yl]sulfonyl}-2,3-dihydro-1,3-benzothiazol-2-one
L306-1265 Screening compound: 3-(propan-2-yl)-6-{[4-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidin-1-yl]sulfonyl}-2,3-dihydro-1,3-benzothiazol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L306-1265
3-(propan-2-yl)-6-{[4-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidin-1-yl]sulfonyl}-2,3-dihydro-1,3-benzothiazol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L306-1265

Molecular Formula

C25H29N3O4S2 (C25 H29 N3 O4 S2)

Compound Name

3-(propan-2-yl)-6-{[4-(1,2,3,4-tetrahydroisoquinoline-2-carbonyl)piperidin-1-yl]sulfonyl}-2,3-dihydro-1,3-benzothiazol-2-one

IUPAC name

3-(propan-2-yl)-6-{[4-(1234-tetrahydroisoquinoline-2-carbonyl)piperidin-1-yl]sulfonyl}-23-dihydro-13-benzothiazol-2-one

SMILES

CC(C)N(c(ccc(S(N(CC1)CCC1C(N(CC1)Cc2c1cccc2)=O)(=O)=O)c1)c1S1)C1=O

InChI

InChI=1S/C25H29N3O4S2/c1-17(2)28-22-8-7-21(15-23(22)33-25(28)30)34(31,32)27-13-10-19(11-14-27)24(29)26-12-9-18-5-3-4-6-20(18)16-26/h3-8,15,17,19H,9-14,16H2,1-2H3

InChI Key

YJMZSPVFOISSHP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27243538

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

499.66

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.463

Distribution Coefficient, logD

4.463

Water Solubility, LogSw

-4.28

Polar Surface Area

63.825

Acid Dissociation Constant (pKa)

22.79

Base Dissociation Constant (pKb)

-2.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.00

L306-1265 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L306-1265 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L306-1265?
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What is the minimum amount of L306-1265 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L306-1265
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L306-1265
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L306-1265 available by request