L308-1530 Screening compound: 3-{3-[4-(piperidine-1-sulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-(1,2,3,4-tetrahydroisoquinolin-2-yl)propan-1-one

L308-1530 Screening compound: 3-{3-[4-(piperidine-1-sulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-(1,2,3,4-tetrahydroisoquinolin-2-yl)propan-1-one
L308-1530 Screening compound: 3-{3-[4-(piperidine-1-sulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-(1,2,3,4-tetrahydroisoquinolin-2-yl)propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L308-1530
3-{3-[4-(piperidine-1-sulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-(1,2,3,4-tetrahydroisoquinolin-2-yl)propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L308-1530

Molecular Formula

C25H28N4O4S (C25 H28 N4 O4 S)

Compound Name

3-{3-[4-(piperidine-1-sulfonyl)phenyl]-1,2,4-oxadiazol-5-yl}-1-(1,2,3,4-tetrahydroisoquinolin-2-yl)propan-1-one

IUPAC name

3-{3-[4-(piperidine-1-sulfonyl)phenyl]-124-oxadiazol-5-yl}-1-(1234-tetrahydroisoquinolin-2-yl)propan-1-one

SMILES

O=C(CCc1nc(-c(cc2)ccc2S(N2CCCCC2)(=O)=O)no1)N(CC1)Cc2c1cccc2

InChI

InChI=1S/C25H28N4O4S/c30-24(28-17-14-19-6-2-3-7-21(19)18-28)13-12-23-26-25(27-33-23)20-8-10-22(11-9-20)34(31,32)29-15-4-1-5-16-29/h2-3,6-11H,1,4-5,12-18H2

InChI Key

LXWITXBNRXUKBQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27243891

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

480.59

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.051

Distribution Coefficient, logD

4.051

Water Solubility, LogSw

-4.13

Polar Surface Area

79.075

Acid Dissociation Constant (pKa)

22.94

Base Dissociation Constant (pKb)

-2.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

L308-1530 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L308-1530 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L308-1530?
Check Price and Availability of L308-1530, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L308-1530 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L308-1530
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L308-1530
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L308-1530 available by request