L309-1236 Screening compound: 4-[(5-cyclobutyl-1,2,4-oxadiazol-3-yl)methyl]-N-(2-fluorophenyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-sulfonamide

L309-1236 Screening compound: 4-[(5-cyclobutyl-1,2,4-oxadiazol-3-yl)methyl]-N-(2-fluorophenyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-sulfonamide
L309-1236 Screening compound: 4-[(5-cyclobutyl-1,2,4-oxadiazol-3-yl)methyl]-N-(2-fluorophenyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L309-1236
4-[(5-cyclobutyl-1,2,4-oxadiazol-3-yl)methyl]-N-(2-fluorophenyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L309-1236

Molecular Formula

C21H19FN4O5S (C21 H19 FN4 O5 S)

Compound Name

4-[(5-cyclobutyl-1,2,4-oxadiazol-3-yl)methyl]-N-(2-fluorophenyl)-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-sulfonamide

IUPAC name

4-[(5-cyclobutyl-124-oxadiazol-3-yl)methyl]-N-(2-fluorophenyl)-3-oxo-34-dihydro-2H-14-benzoxazine-6-sulfonamide

SMILES

O=C1N(Cc2noc(C3CCC3)n2)c(cc(cc2)S(Nc(cccc3)c3F)(=O)=O)c2OC1

InChI

InChI=1S/C21H19FN4O5S/c22-15-6-1-2-7-16(15)25-32(28,29)14-8-9-18-17(10-14)26(20(27)12-30-18)11-19-23-21(31-24-19)13-4-3-5-13/h1-2,6-10,13,25H,3-5,11-12H2

InChI Key

IQHJNYDTGMARFR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27244153

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

458.47

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.838

Distribution Coefficient, logD

2.680

Water Solubility, LogSw

-3.45

Polar Surface Area

97.211

Acid Dissociation Constant (pKa)

7.76

Base Dissociation Constant (pKb)

-3.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

L309-1236 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Protein-Protein Interaction Library (218420 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Agro:
  • Agro
Mechanism of action:
  • PPI modulators
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L309-1236 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L309-1236?
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What is the minimum amount of L309-1236 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L309-1236
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L309-1236
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L309-1236 available by request