L309-1285 Screening compound: 4-[(5-cyclobutyl-1,2,4-oxadiazol-3-yl)methyl]-N-cyclopropyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-sulfonamide

L309-1285 Screening compound: 4-[(5-cyclobutyl-1,2,4-oxadiazol-3-yl)methyl]-N-cyclopropyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-sulfonamide
L309-1285 Screening compound: 4-[(5-cyclobutyl-1,2,4-oxadiazol-3-yl)methyl]-N-cyclopropyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L309-1285
4-[(5-cyclobutyl-1,2,4-oxadiazol-3-yl)methyl]-N-cyclopropyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L309-1285

Molecular Formula

C18H20N4O5S (C18 H20 N4 O5 S)

Compound Name

4-[(5-cyclobutyl-1,2,4-oxadiazol-3-yl)methyl]-N-cyclopropyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-6-sulfonamide

IUPAC name

4-[(5-cyclobutyl-124-oxadiazol-3-yl)methyl]-N-cyclopropyl-3-oxo-34-dihydro-2H-14-benzoxazine-6-sulfonamide

SMILES

O=C1N(Cc2noc(C3CCC3)n2)c(cc(cc2)S(NC3CC3)(=O)=O)c2OC1

InChI

InChI=1S/C18H20N4O5S/c23-17-10-26-15-7-6-13(28(24,25)21-12-4-5-12)8-14(15)22(17)9-16-19-18(27-20-16)11-2-1-3-11/h6-8,11-12,21H,1-5,9-10H2

InChI Key

HBVOBQCTWJOBQE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27244175

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

404.45

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.839

Distribution Coefficient, logD

1.839

Water Solubility, LogSw

-2.76

Polar Surface Area

99.287

Acid Dissociation Constant (pKa)

11.34

Base Dissociation Constant (pKb)

-3.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

L309-1285 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Others
  • Kinases
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L309-1285 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L309-1285?
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What is the minimum amount of L309-1285 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L309-1285
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L309-1285
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L309-1285 available by request