L317-0165 Screening compound: 1-[4-(5-chloro-1H-indol-2-yl)phenyl]-3-(2,4-difluorophenyl)urea

L317-0165 Screening compound: 1-[4-(5-chloro-1H-indol-2-yl)phenyl]-3-(2,4-difluorophenyl)urea
L317-0165 Screening compound: 1-[4-(5-chloro-1H-indol-2-yl)phenyl]-3-(2,4-difluorophenyl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L317-0165
1-[4-(5-chloro-1H-indol-2-yl)phenyl]-3-(2,4-difluorophenyl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L317-0165

Molecular Formula

C21H14ClF2N3O (C21 H14 ClF2 N3 O)

Compound Name

1-[4-(5-chloro-1H-indol-2-yl)phenyl]-3-(2,4-difluorophenyl)urea

IUPAC name

1-[4-(5-chloro-1H-indol-2-yl)phenyl]-3-(24-difluorophenyl)urea

SMILES

O=C(Nc(cc1)ccc1-c1cc(cc(cc2)Cl)c2[nH]1)Nc(ccc(F)c1)c1F

InChI

InChI=1S/C21H14ClF2N3O/c22-14-3-7-18-13(9-14)10-20(26-18)12-1-5-16(6-2-12)25-21(28)27-19-8-4-15(23)11-17(19)24/h1-11,26H,(H2,25,27,28)

InChI Key

FXBSKVMKWNCALQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15123688

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

397.81

Hydrogen Bond Acceptors Count

2.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.415

Distribution Coefficient, logD

6.414

Water Solubility, LogSw

-6.58

Polar Surface Area

40.921

Acid Dissociation Constant (pKa)

9.95

Base Dissociation Constant (pKb)

-1.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

L317-0165 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Indole Derivatives (10091 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L317-0165 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L317-0165?
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What is the minimum amount of L317-0165 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L317-0165
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L317-0165
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L317-0165 available by request