L321-0034 Screening compound: 6-{4-[4-(2-fluorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

L321-0034 Screening compound: 6-{4-[4-(2-fluorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
L321-0034 Screening compound: 6-{4-[4-(2-fluorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound L321-0034
6-{4-[4-(2-fluorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L321-0034

Molecular Formula

C22H28FN5O3 (C22 H28 FN5 O3)

Compound Name

6-{4-[4-(2-fluorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-1,3-dimethyl-1,2,3,4-tetrahydropyrimidine-2,4-dione

IUPAC name

6-{4-[4-(2-fluorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-13-dimethyl-1234-tetrahydropyrimidine-24-dione

SMILES

CN(C(C=C(N1C)N(CC2)CCC2C(N(CC2)CCN2c(cccc2)c2F)=O)=O)C1=O

InChI

InChI=1S/C22H28FN5O3/c1-24-19(15-20(29)25(2)22(24)31)27-9-7-16(8-10-27)21(30)28-13-11-26(12-14-28)18-6-4-3-5-17(18)23/h3-6,15-16H,7-14H2,1-2H3

InChI Key

RZGUMJLBIJHOGA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15123951

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

429.49

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.875

Distribution Coefficient, logD

1.875

Water Solubility, LogSw

-2.07

Polar Surface Area

55.332

Acid Dissociation Constant (pKa)

23.62

Base Dissociation Constant (pKb)

4.98

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

L321-0034 in Drug Discovery

Included in Screening Libraries

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L321-0034 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L321-0034?
Check Price and Availability of L321-0034, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L321-0034 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L321-0034
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L321-0034
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L321-0034 available by request