L322-0380 Screening compound: N-[1,3-dimethyl-6-(4-methylbenzenesulfonyl)-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]-2-fluorobenzamide

L322-0380 Screening compound: N-[1,3-dimethyl-6-(4-methylbenzenesulfonyl)-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]-2-fluorobenzamide
L322-0380 Screening compound: N-[1,3-dimethyl-6-(4-methylbenzenesulfonyl)-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]-2-fluorobenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L322-0380
N-[1,3-dimethyl-6-(4-methylbenzenesulfonyl)-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]-2-fluorobenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L322-0380

Molecular Formula

C23H20FN3O4S (C23 H20 FN3 O4 S)

Compound Name

N-[1,3-dimethyl-6-(4-methylbenzenesulfonyl)-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]-2-fluorobenzamide

IUPAC name

N-[13-dimethyl-6-(4-methylbenzenesulfonyl)-2-oxo-23-dihydro-1H-13-benzodiazol-5-yl]-2-fluorobenzamide

SMILES

Cc(cc1)ccc1S(c(cc(c(N1C)c2)N(C)C1=O)c2NC(c(cccc1)c1F)=O)(=O)=O

InChI

InChI=1S/C23H20FN3O4S/c1-14-8-10-15(11-9-14)32(30,31)21-13-20-19(26(2)23(29)27(20)3)12-18(21)25-22(28)16-6-4-5-7-17(16)24/h4-13H,1-3H3,(H,25,28)

InChI Key

OIQWTRRWCUZHRZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27244958

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

453.49

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.063

Distribution Coefficient, logD

3.967

Water Solubility, LogSw

-4.19

Polar Surface Area

69.817

Acid Dissociation Constant (pKa)

8.01

Base Dissociation Constant (pKb)

-4.38

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

L322-0380 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Hsp90-Targeted Library (11355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system

References: we are preparing a list of scientific research reports with L322-0380 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L322-0380?
Check Price and Availability of L322-0380, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L322-0380 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L322-0380
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L322-0380
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L322-0380 available by request