L322-0443 Screening compound: 2,6-difluoro-N-[6-(4-fluorobenzenesulfonyl)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]benzamide

L322-0443 Screening compound: 2,6-difluoro-N-[6-(4-fluorobenzenesulfonyl)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]benzamide
L322-0443 Screening compound: 2,6-difluoro-N-[6-(4-fluorobenzenesulfonyl)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L322-0443
2,6-difluoro-N-[6-(4-fluorobenzenesulfonyl)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L322-0443

Molecular Formula

C22H16F3N3O4S (C22 H16 F3 N3 O4 S)

Compound Name

2,6-difluoro-N-[6-(4-fluorobenzenesulfonyl)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]benzamide

IUPAC name

26-difluoro-N-[6-(4-fluorobenzenesulfonyl)-13-dimethyl-2-oxo-23-dihydro-1H-13-benzodiazol-5-yl]benzamide

SMILES

CN(c(c(N1C)c2)cc(NC(c(c(F)ccc3)c3F)=O)c2S(c(cc2)ccc2F)(=O)=O)C1=O

InChI

InChI=1S/C22H16F3N3O4S/c1-27-17-10-16(26-21(29)20-14(24)4-3-5-15(20)25)19(11-18(17)28(2)22(27)30)33(31,32)13-8-6-12(23)7-9-13/h3-11H,1-2H3,(H,26,29)

InChI Key

JBSQKGHFOLWPFJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27244999

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

475.45

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.980

Distribution Coefficient, logD

3.481

Water Solubility, LogSw

-4.37

Polar Surface Area

69.817

Acid Dissociation Constant (pKa)

7.07

Base Dissociation Constant (pKb)

-4.38

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.10

L322-0443 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anti-Inflammatory Library (24602 compounds)

Anticancer Library (62698 compounds)

Hsp90-Targeted Library (11355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system

References: we are preparing a list of scientific research reports with L322-0443 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L322-0443?
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What is the minimum amount of L322-0443 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L322-0443
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L322-0443
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L322-0443 available by request