L322-0445 Screening compound: N-[6-(4-fluorobenzenesulfonyl)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]-2-(4-methylphenyl)acetamide

L322-0445 Screening compound: N-[6-(4-fluorobenzenesulfonyl)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]-2-(4-methylphenyl)acetamide
L322-0445 Screening compound: N-[6-(4-fluorobenzenesulfonyl)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]-2-(4-methylphenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L322-0445
N-[6-(4-fluorobenzenesulfonyl)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]-2-(4-methylphenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L322-0445

Molecular Formula

C24H22FN3O4S (C24 H22 FN3 O4 S)

Compound Name

N-[6-(4-fluorobenzenesulfonyl)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]-2-(4-methylphenyl)acetamide

IUPAC name

N-[6-(4-fluorobenzenesulfonyl)-13-dimethyl-2-oxo-23-dihydro-1H-13-benzodiazol-5-yl]-2-(4-methylphenyl)acetamide

SMILES

Cc1ccc(CC(Nc(cc(c(N2C)c3)N(C)C2=O)c3S(c(cc2)ccc2F)(=O)=O)=O)cc1

InChI

InChI=1S/C24H22FN3O4S/c1-15-4-6-16(7-5-15)12-23(29)26-19-13-20-21(28(3)24(30)27(20)2)14-22(19)33(31,32)18-10-8-17(25)9-11-18/h4-11,13-14H,12H2,1-3H3,(H,26,29)

InChI Key

MCHOOMJKJNBFMS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27245000

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

467.52

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.799

Distribution Coefficient, logD

3.798

Water Solubility, LogSw

-3.94

Polar Surface Area

69.604

Acid Dissociation Constant (pKa)

9.83

Base Dissociation Constant (pKb)

-3.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

L322-0445 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L322-0445 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L322-0445?
Check Price and Availability of L322-0445, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L322-0445 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L322-0445
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L322-0445
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L322-0445 available by request