L322-0458 Screening compound: 2-(2,4-dimethylphenoxy)-N-[6-(4-fluorobenzenesulfonyl)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]acetamide

L322-0458 Screening compound: 2-(2,4-dimethylphenoxy)-N-[6-(4-fluorobenzenesulfonyl)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]acetamide
L322-0458 Screening compound: 2-(2,4-dimethylphenoxy)-N-[6-(4-fluorobenzenesulfonyl)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L322-0458
2-(2,4-dimethylphenoxy)-N-[6-(4-fluorobenzenesulfonyl)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L322-0458

Molecular Formula

C25H24FN3O5S (C25 H24 FN3 O5 S)

Compound Name

2-(2,4-dimethylphenoxy)-N-[6-(4-fluorobenzenesulfonyl)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]acetamide

IUPAC name

2-(24-dimethylphenoxy)-N-[6-(4-fluorobenzenesulfonyl)-13-dimethyl-2-oxo-23-dihydro-1H-13-benzodiazol-5-yl]acetamide

SMILES

Cc(cc1)cc(C)c1OCC(Nc(cc(c(N1C)c2)N(C)C1=O)c2S(c(cc1)ccc1F)(=O)=O)=O

InChI

InChI=1S/C25H24FN3O5S/c1-15-5-10-22(16(2)11-15)34-14-24(30)27-19-12-20-21(29(4)25(31)28(20)3)13-23(19)35(32,33)18-8-6-17(26)7-9-18/h5-13H,14H2,1-4H3,(H,27,30)

InChI Key

IMNLAHSXRJRFAM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27245011

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

497.55

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.646

Distribution Coefficient, logD

4.646

Water Solubility, LogSw

-4.55

Polar Surface Area

77.190

Acid Dissociation Constant (pKa)

10.40

Base Dissociation Constant (pKb)

-3.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

L322-0458 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anticancer Library (62698 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Hsp90-Targeted Library (11355 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L322-0458 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L322-0458?
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What is the minimum amount of L322-0458 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L322-0458
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L322-0458
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L322-0458 available by request