L322-0535 Screening compound: N-[6-(4-methoxybenzenesulfonyl)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]thiophene-2-carboxamide

L322-0535 Screening compound: N-[6-(4-methoxybenzenesulfonyl)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]thiophene-2-carboxamide
L322-0535 Screening compound: N-[6-(4-methoxybenzenesulfonyl)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]thiophene-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L322-0535
N-[6-(4-methoxybenzenesulfonyl)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]thiophene-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L322-0535

Molecular Formula

C21H19N3O5S2 (C21 H19 N3 O5 S2)

Compound Name

N-[6-(4-methoxybenzenesulfonyl)-1,3-dimethyl-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-5-yl]thiophene-2-carboxamide

IUPAC name

N-[6-(4-methoxybenzenesulfonyl)-13-dimethyl-2-oxo-23-dihydro-1H-13-benzodiazol-5-yl]thiophene-2-carboxamide

SMILES

CN(c(c(N1C)c2)cc(NC(c3cccs3)=O)c2S(c(cc2)ccc2OC)(=O)=O)C1=O

InChI

InChI=1S/C21H19N3O5S2/c1-23-16-11-15(22-20(25)18-5-4-10-30-18)19(12-17(16)24(2)21(23)26)31(27,28)14-8-6-13(29-3)7-9-14/h4-12H,1-3H3,(H,22,25)

InChI Key

IXFKVMPFHKMSPH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27245051

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

457.53

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.551

Distribution Coefficient, logD

3.550

Water Solubility, LogSw

-4.01

Polar Surface Area

78.379

Acid Dissociation Constant (pKa)

9.84

Base Dissociation Constant (pKb)

-3.75

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

L322-0535 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anti-Inflammatory Library (24602 compounds)

Anticancer Library (62698 compounds)

Antiviral Library (67538 compounds)

Hsp90-Targeted Library (11355 compounds)

KRAS-Targeted Library (16000 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Immune system
  • Cancer
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Kinases
  • Kinases
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L322-0535 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L322-0535?
Check Price and Availability of L322-0535, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L322-0535 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L322-0535
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L322-0535
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L322-0535 available by request