L324-0642 Screening compound: 2-{[1-(4-fluorophenyl)-6-oxo-1,6-dihydropyridazin-3-yl]oxy}-N-[(3-methoxyphenyl)methyl]propanamide

L324-0642 Screening compound: 2-{[1-(4-fluorophenyl)-6-oxo-1,6-dihydropyridazin-3-yl]oxy}-N-[(3-methoxyphenyl)methyl]propanamide
L324-0642 Screening compound: 2-{[1-(4-fluorophenyl)-6-oxo-1,6-dihydropyridazin-3-yl]oxy}-N-[(3-methoxyphenyl)methyl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L324-0642
2-{[1-(4-fluorophenyl)-6-oxo-1,6-dihydropyridazin-3-yl]oxy}-N-[(3-methoxyphenyl)methyl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L324-0642

Molecular Formula

C21H20FN3O4 (C21 H20 FN3 O4)

Compound Name

2-{[1-(4-fluorophenyl)-6-oxo-1,6-dihydropyridazin-3-yl]oxy}-N-[(3-methoxyphenyl)methyl]propanamide

IUPAC name

2-{[1-(4-fluorophenyl)-6-oxo-16-dihydropyridazin-3-yl]oxy}-N-[(3-methoxyphenyl)methyl]propanamide

SMILES

CC(C(NCc1cc(OC)ccc1)=O)OC(C=C1)=NN(c(cc2)ccc2F)C1=O

InChI

InChI=1S/C21H20FN3O4/c1-14(21(27)23-13-15-4-3-5-18(12-15)28-2)29-19-10-11-20(26)25(24-19)17-8-6-16(22)7-9-17/h3-12,14H,13H2,1-2H3,(H,23,27)/t14-/m0/s1

InChI Key

LAZLDQHAIXVPIN-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD15124197

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

397.41

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.408

Distribution Coefficient, logD

2.408

Water Solubility, LogSw

-2.82

Polar Surface Area

67.231

Acid Dissociation Constant (pKa)

13.60

Base Dissociation Constant (pKb)

0.21

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

19.00

L324-0642 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L324-0642 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L324-0642?
Check Price and Availability of L324-0642, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L324-0642 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L324-0642
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L324-0642
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L324-0642 available by request