L325-0340 Screening compound: 2-[3-(4-benzylpiperazine-1-carbonyl)piperidin-1-yl]-5-(4-methylphenyl)pyrimidine

L325-0340 Screening compound: 2-[3-(4-benzylpiperazine-1-carbonyl)piperidin-1-yl]-5-(4-methylphenyl)pyrimidine
L325-0340 Screening compound: 2-[3-(4-benzylpiperazine-1-carbonyl)piperidin-1-yl]-5-(4-methylphenyl)pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound L325-0340
2-[3-(4-benzylpiperazine-1-carbonyl)piperidin-1-yl]-5-(4-methylphenyl)pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L325-0340

Molecular Formula

C28H33N5O (C28 H33 N5 O)

Compound Name

2-[3-(4-benzylpiperazine-1-carbonyl)piperidin-1-yl]-5-(4-methylphenyl)pyrimidine

IUPAC name

2-[3-(4-benzylpiperazine-1-carbonyl)piperidin-1-yl]-5-(4-methylphenyl)pyrimidine

SMILES

Cc(cc1)ccc1-c1cnc(N(CCC2)CC2C(N2CCN(Cc3ccccc3)CC2)=O)nc1

InChI

InChI=1S/C28H33N5O/c1-22-9-11-24(12-10-22)26-18-29-28(30-19-26)33-13-5-8-25(21-33)27(34)32-16-14-31(15-17-32)20-23-6-3-2-4-7-23/h2-4,6-7,9-12,18-19,25H,5,8,13-17,20-21H2,1H3/t25-/m0/s1

InChI Key

XJIQMBDQJPXFPE-VWLOTQADSA-N

MDL Number (MFCD)

MFCD27245292

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

455.6

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.005

Distribution Coefficient, logD

3.953

Water Solubility, LogSw

-4.12

Polar Surface Area

42.083

Acid Dissociation Constant (pKa)

20.27

Base Dissociation Constant (pKb)

6.50

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

39.30

L325-0340 in Drug Discovery

Included in Screening Libraries

Autophagy-Targeted Library (4564 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L325-0340 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L325-0340?
Check Price and Availability of L325-0340, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L325-0340 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L325-0340
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L325-0340
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L325-0340 available by request