L325-0552 Screening compound: N-[2-(4-ethylpiperazin-1-yl)ethyl]-1-[5-(3-fluorophenyl)pyrimidin-2-yl]piperidine-3-carboxamide

L325-0552 Screening compound: N-[2-(4-ethylpiperazin-1-yl)ethyl]-1-[5-(3-fluorophenyl)pyrimidin-2-yl]piperidine-3-carboxamide
L325-0552 Screening compound: N-[2-(4-ethylpiperazin-1-yl)ethyl]-1-[5-(3-fluorophenyl)pyrimidin-2-yl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L325-0552
N-[2-(4-ethylpiperazin-1-yl)ethyl]-1-[5-(3-fluorophenyl)pyrimidin-2-yl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L325-0552

Molecular Formula

C24H33FN6O (C24 H33 FN6 O)

Compound Name

N-[2-(4-ethylpiperazin-1-yl)ethyl]-1-[5-(3-fluorophenyl)pyrimidin-2-yl]piperidine-3-carboxamide

IUPAC name

N-[2-(4-ethylpiperazin-1-yl)ethyl]-1-[5-(3-fluorophenyl)pyrimidin-2-yl]piperidine-3-carboxamide

SMILES

CCN1CCN(CCNC(C(CCC2)CN2c(nc2)ncc2-c2cccc(F)c2)=O)CC1

InChI

InChI=1S/C24H33FN6O/c1-2-29-11-13-30(14-12-29)10-8-26-23(32)20-6-4-9-31(18-20)24-27-16-21(17-28-24)19-5-3-7-22(25)15-19/h3,5,7,15-17,20H,2,4,6,8-14,18H2,1H3,(H,26,32)/t20-/m0/s1

InChI Key

CBXNIRFQNJUTNJ-FQEVSTJZSA-N

MDL Number (MFCD)

MFCD27245419

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

440.56

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.042

Distribution Coefficient, logD

1.250

Water Solubility, LogSw

-2.57

Polar Surface Area

53.668

Acid Dissociation Constant (pKa)

13.28

Base Dissociation Constant (pKb)

8.12

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

54.20

L325-0552 in Drug Discovery

Included in Screening Libraries

MCL1 Targeted Library (12200 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L325-0552 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L325-0552?
Check Price and Availability of L325-0552, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L325-0552 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L325-0552
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L325-0552
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L325-0552 available by request