L327-0831 Screening compound: 4-[5-(CYCLOPENTYLAMINO)-2-(4-PROPYLPIPERAZIN-1-YL)IMIDAZO[2,1-B][1,3,4]THIADIAZOL-6-YL]PHENOL

L327-0831 Screening compound: 4-[5-(CYCLOPENTYLAMINO)-2-(4-PROPYLPIPERAZIN-1-YL)IMIDAZO[2,1-B][1,3,4]THIADIAZOL-6-YL]PHENOL
L327-0831 Screening compound: 4-[5-(CYCLOPENTYLAMINO)-2-(4-PROPYLPIPERAZIN-1-YL)IMIDAZO[2,1-B][1,3,4]THIADIAZOL-6-YL]PHENOL alternative view

Chemical Structure Depiction of ChemDiv screening compound L327-0831
4-[5-(CYCLOPENTYLAMINO)-2-(4-PROPYLPIPERAZIN-1-YL)IMIDAZO[2,1-B][1,3,4]THIADIAZOL-6-YL]PHENOL

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L327-0831

Molecular Formula

C22H30N6OS (C22 H30 N6 OS)

Compound Name

4-[5-(CYCLOPENTYLAMINO)-2-(4-PROPYLPIPERAZIN-1-YL)IMIDAZO[2,1-B][1,3,4]THIADIAZOL-6-YL]PHENOL

IUPAC name

n/a

SMILES

CCCN(CC1)CCN1c(s1)nn2c1nc(-c(cc1)ccc1O)c2NC1CCCC1

InChI

InChI=1S/C22H30N6OS/c1-2-11-26-12-14-27(15-13-26)22-25-28-20(23-17-5-3-4-6-17)19(24-21(28)30-22)16-7-9-18(29)10-8-16/h7-10,17,23,29H,2-6,11-15H2,1H3

InChI Key

GYQVXOOOSABFNH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27245708

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

426.59

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.042

Distribution Coefficient, logD

3.172

Water Solubility, LogSw

-3.99

Polar Surface Area

56.183

Acid Dissociation Constant (pKa)

9.31

Base Dissociation Constant (pKb)

8.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

54.50

L327-0831 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system

References: we are preparing a list of scientific research reports with L327-0831 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L327-0831?
Check Price and Availability of L327-0831, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L327-0831 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L327-0831
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L327-0831
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L327-0831 available by request