L327-0874 Screening compound: N-cyclohexyl-6-(3,5-dimethoxyphenyl)-2-(4-propylpiperazin-1-yl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine

L327-0874 Screening compound: N-cyclohexyl-6-(3,5-dimethoxyphenyl)-2-(4-propylpiperazin-1-yl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine
L327-0874 Screening compound: N-cyclohexyl-6-(3,5-dimethoxyphenyl)-2-(4-propylpiperazin-1-yl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound L327-0874
N-cyclohexyl-6-(3,5-dimethoxyphenyl)-2-(4-propylpiperazin-1-yl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L327-0874

Molecular Formula

C25H36N6O2S (C25 H36 N6 O2 S)

Compound Name

N-cyclohexyl-6-(3,5-dimethoxyphenyl)-2-(4-propylpiperazin-1-yl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine

IUPAC name

N-cyclohexyl-6-(35-dimethoxyphenyl)-2-(4-propylpiperazin-1-yl)imidazo[21-b][134]thiadiazol-5-amine

SMILES

CCCN(CC1)CCN1c(s1)nn2c1nc(-c1cc(OC)cc(OC)c1)c2NC1CCCCC1

InChI

InChI=1S/C25H36N6O2S/c1-4-10-29-11-13-30(14-12-29)25-28-31-23(26-19-8-6-5-7-9-19)22(27-24(31)34-25)18-15-20(32-2)17-21(16-18)33-3/h15-17,19,26H,4-14H2,1-3H3

InChI Key

PTVHXGYMHMHYKZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27245714

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

484.67

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.346

Distribution Coefficient, logD

4.476

Water Solubility, LogSw

-5.30

Polar Surface Area

53.288

Acid Dissociation Constant (pKa)

22.99

Base Dissociation Constant (pKb)

8.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

60.00

L327-0874 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L327-0874 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L327-0874?
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What is the minimum amount of L327-0874 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L327-0874
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L327-0874
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L327-0874 available by request