L327-1813 Screening compound: 2-(4-cyclohexylpiperazin-1-yl)-N-cyclopentyl-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine

L327-1813 Screening compound: 2-(4-cyclohexylpiperazin-1-yl)-N-cyclopentyl-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine
L327-1813 Screening compound: 2-(4-cyclohexylpiperazin-1-yl)-N-cyclopentyl-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound L327-1813
2-(4-cyclohexylpiperazin-1-yl)-N-cyclopentyl-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L327-1813

Molecular Formula

C25H33FN6S (C25 H33 FN6 S)

Compound Name

2-(4-cyclohexylpiperazin-1-yl)-N-cyclopentyl-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine

IUPAC name

2-(4-cyclohexylpiperazin-1-yl)-N-cyclopentyl-6-(4-fluorophenyl)imidazo[21-b][134]thiadiazol-5-amine

SMILES

Fc(cc1)ccc1-c1c(NC2CCCC2)n2nc(N(CC3)CCN3C3CCCCC3)sc2n1

InChI

InChI=1S/C25H33FN6S/c26-19-12-10-18(11-13-19)22-23(27-20-6-4-5-7-20)32-24(28-22)33-25(29-32)31-16-14-30(15-17-31)21-8-2-1-3-9-21/h10-13,20-21,27H,1-9,14-17H2

InChI Key

NCINYRMVMYDPMD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27245735

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

468.64

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.718

Distribution Coefficient, logD

4.901

Water Solubility, LogSw

-5.98

Polar Surface Area

37.869

Acid Dissociation Constant (pKa)

23.04

Base Dissociation Constant (pKb)

8.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

60.00

L327-1813 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L327-1813 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L327-1813?
Check Price and Availability of L327-1813, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L327-1813 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L327-1813
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L327-1813
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L327-1813 available by request