L327-1825 Screening compound: 5-[2-(4-cyclohexylpiperazin-1-yl)-5-(cyclopentylamino)imidazo[2,1-b][1,3,4]thiadiazol-6-yl]-2-methoxyphenol

L327-1825 Screening compound: 5-[2-(4-cyclohexylpiperazin-1-yl)-5-(cyclopentylamino)imidazo[2,1-b][1,3,4]thiadiazol-6-yl]-2-methoxyphenol
L327-1825 Screening compound: 5-[2-(4-cyclohexylpiperazin-1-yl)-5-(cyclopentylamino)imidazo[2,1-b][1,3,4]thiadiazol-6-yl]-2-methoxyphenol alternative view

Chemical Structure Depiction of ChemDiv screening compound L327-1825
5-[2-(4-cyclohexylpiperazin-1-yl)-5-(cyclopentylamino)imidazo[2,1-b][1,3,4]thiadiazol-6-yl]-2-methoxyphenol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L327-1825

Molecular Formula

C26H36N6O2S (C26 H36 N6 O2 S)

Compound Name

5-[2-(4-cyclohexylpiperazin-1-yl)-5-(cyclopentylamino)imidazo[2,1-b][1,3,4]thiadiazol-6-yl]-2-methoxyphenol

IUPAC name

5-[2-(4-cyclohexylpiperazin-1-yl)-5-(cyclopentylamino)imidazo[21-b][134]thiadiazol-6-yl]-2-methoxyphenol

SMILES

COc(ccc(-c1c(NC2CCCC2)n2nc(N(CC3)CCN3C3CCCCC3)sc2n1)c1)c1O

InChI

InChI=1S/C26H36N6O2S/c1-34-22-12-11-18(17-21(22)33)23-24(27-19-7-5-6-8-19)32-25(28-23)35-26(29-32)31-15-13-30(14-16-31)20-9-3-2-4-10-20/h11-12,17,19-20,27,33H,2-10,13-16H2,1H3

InChI Key

BJNOFNZTPNXUEO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27245739

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

496.68

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.326

Distribution Coefficient, logD

4.509

Water Solubility, LogSw

-5.13

Polar Surface Area

62.048

Acid Dissociation Constant (pKa)

9.48

Base Dissociation Constant (pKb)

8.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

61.50

L327-1825 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Hsp90-Targeted Library (11355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system

References: we are preparing a list of scientific research reports with L327-1825 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L327-1825?
Check Price and Availability of L327-1825, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L327-1825 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L327-1825
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L327-1825
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L327-1825 available by request