L327-2336 Screening compound: 2-(4-cyclobutanecarbonylpiperazin-1-yl)-N-cyclopentyl-6-(4-ethylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine

L327-2336 Screening compound: 2-(4-cyclobutanecarbonylpiperazin-1-yl)-N-cyclopentyl-6-(4-ethylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine
L327-2336 Screening compound: 2-(4-cyclobutanecarbonylpiperazin-1-yl)-N-cyclopentyl-6-(4-ethylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound L327-2336
2-(4-cyclobutanecarbonylpiperazin-1-yl)-N-cyclopentyl-6-(4-ethylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L327-2336

Molecular Formula

C26H34N6OS (C26 H34 N6 OS)

Compound Name

2-(4-cyclobutanecarbonylpiperazin-1-yl)-N-cyclopentyl-6-(4-ethylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine

IUPAC name

2-(4-cyclobutanecarbonylpiperazin-1-yl)-N-cyclopentyl-6-(4-ethylphenyl)imidazo[21-b][134]thiadiazol-5-amine

SMILES

CCc(cc1)ccc1-c1c(NC2CCCC2)n2nc(N(CC3)CCN3C(C3CCC3)=O)sc2n1

InChI

InChI=1S/C26H34N6OS/c1-2-18-10-12-19(13-11-18)22-23(27-21-8-3-4-9-21)32-25(28-22)34-26(29-32)31-16-14-30(15-17-31)24(33)20-6-5-7-20/h10-13,20-21,27H,2-9,14-17H2,1H3

InChI Key

HNQAYTWJFMTSLX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27245758

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

478.66

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.069

Distribution Coefficient, logD

5.068

Water Solubility, LogSw

-4.61

Polar Surface Area

51.755

Acid Dissociation Constant (pKa)

23.04

Base Dissociation Constant (pKb)

4.91

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

57.70

L327-2336 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L327-2336 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L327-2336?
Check Price and Availability of L327-2336, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L327-2336 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L327-2336
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L327-2336
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L327-2336 available by request