L327-2966 Screening compound: 2-(4-cyclohexanecarbonylpiperazin-1-yl)-N-cyclopentyl-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine

L327-2966 Screening compound: 2-(4-cyclohexanecarbonylpiperazin-1-yl)-N-cyclopentyl-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine
L327-2966 Screening compound: 2-(4-cyclohexanecarbonylpiperazin-1-yl)-N-cyclopentyl-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound L327-2966
2-(4-cyclohexanecarbonylpiperazin-1-yl)-N-cyclopentyl-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L327-2966

Molecular Formula

C26H33FN6OS (C26 H33 FN6 OS)

Compound Name

2-(4-cyclohexanecarbonylpiperazin-1-yl)-N-cyclopentyl-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine

IUPAC name

2-(4-cyclohexanecarbonylpiperazin-1-yl)-N-cyclopentyl-6-(4-fluorophenyl)imidazo[21-b][134]thiadiazol-5-amine

SMILES

O=C(C1CCCCC1)N(CC1)CCN1c(s1)nn2c1nc(-c(cc1)ccc1F)c2NC1CCCC1

InChI

InChI=1S/C26H33FN6OS/c27-20-12-10-18(11-13-20)22-23(28-21-8-4-5-9-21)33-25(29-22)35-26(30-33)32-16-14-31(15-17-32)24(34)19-6-2-1-3-7-19/h10-13,19,21,28H,1-9,14-17H2

InChI Key

DSFOTGGFJUJQKI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27245796

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

496.65

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.477

Distribution Coefficient, logD

5.477

Water Solubility, LogSw

-5.64

Polar Surface Area

51.424

Acid Dissociation Constant (pKa)

23.04

Base Dissociation Constant (pKb)

3.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

57.70

L327-2966 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L327-2966 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L327-2966?
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What is the minimum amount of L327-2966 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L327-2966
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L327-2966
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L327-2966 available by request