L327-3084 Screening compound: N-tert-butyl-2-[4-(4-fluorobenzoyl)piperazin-1-yl]-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine

L327-3084 Screening compound: N-tert-butyl-2-[4-(4-fluorobenzoyl)piperazin-1-yl]-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine
L327-3084 Screening compound: N-tert-butyl-2-[4-(4-fluorobenzoyl)piperazin-1-yl]-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound L327-3084
N-tert-butyl-2-[4-(4-fluorobenzoyl)piperazin-1-yl]-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L327-3084

Molecular Formula

C25H26F2N6OS (C25 H26 F2 N6 OS)

Compound Name

N-tert-butyl-2-[4-(4-fluorobenzoyl)piperazin-1-yl]-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-5-amine

IUPAC name

N-tert-butyl-2-[4-(4-fluorobenzoyl)piperazin-1-yl]-6-(4-fluorophenyl)imidazo[21-b][134]thiadiazol-5-amine

SMILES

CC(C)(C)Nc1c(-c(cc2)ccc2F)nc2sc(N(CC3)CCN3C(c(cc3)ccc3F)=O)nn12

InChI

InChI=1S/C25H26F2N6OS/c1-25(2,3)29-21-20(16-4-8-18(26)9-5-16)28-23-33(21)30-24(35-23)32-14-12-31(13-15-32)22(34)17-6-10-19(27)11-7-17/h4-11,29H,12-15H2,1-3H3

InChI Key

CPKQAUWJPQMHEI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27245821

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

496.58

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.803

Distribution Coefficient, logD

4.803

Water Solubility, LogSw

-4.51

Polar Surface Area

50.236

Acid Dissociation Constant (pKa)

21.97

Base Dissociation Constant (pKb)

3.59

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

L327-3084 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L327-3084 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L327-3084?
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What is the minimum amount of L327-3084 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L327-3084
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L327-3084
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L327-3084 available by request