L327-4997 Screening compound: N-tert-butyl-2-[4-(2-methoxybenzoyl)piperazin-1-yl]-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-amine

L327-4997 Screening compound: N-tert-butyl-2-[4-(2-methoxybenzoyl)piperazin-1-yl]-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-amine
L327-4997 Screening compound: N-tert-butyl-2-[4-(2-methoxybenzoyl)piperazin-1-yl]-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound L327-4997
N-tert-butyl-2-[4-(2-methoxybenzoyl)piperazin-1-yl]-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L327-4997

Molecular Formula

C26H30N6O2S (C26 H30 N6 O2 S)

Compound Name

N-tert-butyl-2-[4-(2-methoxybenzoyl)piperazin-1-yl]-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-5-amine

IUPAC name

N-tert-butyl-2-[4-(2-methoxybenzoyl)piperazin-1-yl]-6-phenylimidazo[21-b][134]thiadiazol-5-amine

SMILES

CC(C)(C)Nc1c(-c2ccccc2)nc2sc(N(CC3)CCN3C(c(cccc3)c3OC)=O)nn12

InChI

InChI=1S/C26H30N6O2S/c1-26(2,3)28-22-21(18-10-6-5-7-11-18)27-24-32(22)29-25(35-24)31-16-14-30(15-17-31)23(33)19-12-8-9-13-20(19)34-4/h5-13,28H,14-17H2,1-4H3

InChI Key

RDDGBTCNICQHPI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27245895

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

490.63

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.523

Distribution Coefficient, logD

4.523

Water Solubility, LogSw

-4.37

Polar Surface Area

57.866

Acid Dissociation Constant (pKa)

21.97

Base Dissociation Constant (pKb)

4.11

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.60

L327-4997 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L327-4997 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L327-4997?
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What is the minimum amount of L327-4997 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L327-4997
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L327-4997
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L327-4997 available by request