L327-5496 Screening compound: 1-{4-[5-(tert-butylamino)-6-(3-methylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazin-1-yl}-2-ethoxyethan-1-one

L327-5496 Screening compound: 1-{4-[5-(tert-butylamino)-6-(3-methylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazin-1-yl}-2-ethoxyethan-1-one
L327-5496 Screening compound: 1-{4-[5-(tert-butylamino)-6-(3-methylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazin-1-yl}-2-ethoxyethan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L327-5496
1-{4-[5-(tert-butylamino)-6-(3-methylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazin-1-yl}-2-ethoxyethan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L327-5496

Molecular Formula

C23H32N6O2S (C23 H32 N6 O2 S)

Compound Name

1-{4-[5-(tert-butylamino)-6-(3-methylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazin-1-yl}-2-ethoxyethan-1-one

IUPAC name

1-{4-[5-(tert-butylamino)-6-(3-methylphenyl)imidazo[21-b][134]thiadiazol-2-yl]piperazin-1-yl}-2-ethoxyethan-1-one

SMILES

CCOCC(N(CC1)CCN1c(s1)nn2c1nc(-c1cc(C)ccc1)c2NC(C)(C)C)=O

InChI

InChI=1S/C23H32N6O2S/c1-6-31-15-18(30)27-10-12-28(13-11-27)22-26-29-20(25-23(3,4)5)19(24-21(29)32-22)17-9-7-8-16(2)14-17/h7-9,14,25H,6,10-13,15H2,1-5H3

InChI Key

QDTMAHVJRHDGCN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27245916

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

456.61

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.757

Distribution Coefficient, logD

3.757

Water Solubility, LogSw

-3.81

Polar Surface Area

58.039

Acid Dissociation Constant (pKa)

22.11

Base Dissociation Constant (pKb)

4.49

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.20

L327-5496 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L327-5496 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L327-5496?
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What is the minimum amount of L327-5496 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L327-5496
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L327-5496
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L327-5496 available by request