L327-8297 Screening compound: 4-[5-(TERT-BUTYLAMINO)-6-(4-ETHYLPHENYL)IMIDAZO[2,1-B][1,3,4]THIADIAZOL-2-YL]-N-(2-METHOXYETHYL)TETRAHYDRO-1(2H)-PYRAZINECARBOXAMIDE

L327-8297 Screening compound: 4-[5-(TERT-BUTYLAMINO)-6-(4-ETHYLPHENYL)IMIDAZO[2,1-B][1,3,4]THIADIAZOL-2-YL]-N-(2-METHOXYETHYL)TETRAHYDRO-1(2H)-PYRAZINECARBOXAMIDE
L327-8297 Screening compound: 4-[5-(TERT-BUTYLAMINO)-6-(4-ETHYLPHENYL)IMIDAZO[2,1-B][1,3,4]THIADIAZOL-2-YL]-N-(2-METHOXYETHYL)TETRAHYDRO-1(2H)-PYRAZINECARBOXAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound L327-8297
4-[5-(TERT-BUTYLAMINO)-6-(4-ETHYLPHENYL)IMIDAZO[2,1-B][1,3,4]THIADIAZOL-2-YL]-N-(2-METHOXYETHYL)TETRAHYDRO-1(2H)-PYRAZINECARBOXAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L327-8297

Molecular Formula

C24H35N7O2S (C24 H35 N7 O2 S)

Compound Name

4-[5-(TERT-BUTYLAMINO)-6-(4-ETHYLPHENYL)IMIDAZO[2,1-B][1,3,4]THIADIAZOL-2-YL]-N-(2-METHOXYETHYL)TETRAHYDRO-1(2H)-PYRAZINECARBOXAMIDE

IUPAC name

4-[5-(tert-butylamino)-6-(4-ethylphenyl)imidazo[21-b][134]thiadiazol-2-yl]-N-(2-methoxyethyl)piperazine-1-carboxamide

SMILES

CCc(cc1)ccc1-c1c(NC(C)(C)C)n2nc(N(CC3)CCN3C(NCCOC)=O)sc2n1

InChI

InChI=1S/C24H35N7O2S/c1-6-17-7-9-18(10-8-17)19-20(27-24(2,3)4)31-22(26-19)34-23(28-31)30-14-12-29(13-15-30)21(32)25-11-16-33-5/h7-10,27H,6,11-16H2,1-5H3,(H,25,32)

InChI Key

KBWCUTOPBQFPJU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27245955

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

485.65

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.640

Distribution Coefficient, logD

4.638

Water Solubility, LogSw

-4.23

Polar Surface Area

68.835

Acid Dissociation Constant (pKa)

15.96

Base Dissociation Constant (pKb)

4.86

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

54.17

L327-8297 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L327-8297 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L327-8297?
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What is the minimum amount of L327-8297 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L327-8297
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L327-8297
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L327-8297 available by request