L327-8488 Screening compound: ethyl 2-({4-[5-(tert-butylamino)-6-(2-methylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazine-1-carbonyl}amino)acetate

L327-8488 Screening compound: ethyl 2-({4-[5-(tert-butylamino)-6-(2-methylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazine-1-carbonyl}amino)acetate
L327-8488 Screening compound: ethyl 2-({4-[5-(tert-butylamino)-6-(2-methylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazine-1-carbonyl}amino)acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound L327-8488
ethyl 2-({4-[5-(tert-butylamino)-6-(2-methylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazine-1-carbonyl}amino)acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L327-8488

Molecular Formula

C24H33N7O3S (C24 H33 N7 O3 S)

Compound Name

ethyl 2-({4-[5-(tert-butylamino)-6-(2-methylphenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]piperazine-1-carbonyl}amino)acetate

IUPAC name

ethyl 2-({4-[5-(tert-butylamino)-6-(2-methylphenyl)imidazo[21-b][134]thiadiazol-2-yl]piperazine-1-carbonyl}amino)acetate

SMILES

CCOC(CNC(N(CC1)CCN1c(s1)nn2c1nc(-c1c(C)cccc1)c2NC(C)(C)C)=O)=O

InChI

InChI=1S/C24H33N7O3S/c1-6-34-18(32)15-25-21(33)29-11-13-30(14-12-29)23-28-31-20(27-24(3,4)5)19(26-22(31)35-23)17-10-8-7-9-16(17)2/h7-10,27H,6,11-15H2,1-5H3,(H,25,33)

InChI Key

SMUCTTVCMHLSPA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27245959

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

499.64

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

3.900

Distribution Coefficient, logD

3.900

Water Solubility, LogSw

-3.90

Polar Surface Area

80.809

Acid Dissociation Constant (pKa)

15.30

Base Dissociation Constant (pKb)

3.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

L327-8488 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L327-8488 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L327-8488?
Check Price and Availability of L327-8488, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L327-8488 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L327-8488
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L327-8488
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L327-8488 available by request