L327-8896 Screening compound: 4-[5-(tert-butylamino)-6-(3-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]-N-(2-methoxyethyl)piperazine-1-carboxamide

L327-8896 Screening compound: 4-[5-(tert-butylamino)-6-(3-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]-N-(2-methoxyethyl)piperazine-1-carboxamide
L327-8896 Screening compound: 4-[5-(tert-butylamino)-6-(3-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]-N-(2-methoxyethyl)piperazine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L327-8896
4-[5-(tert-butylamino)-6-(3-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]-N-(2-methoxyethyl)piperazine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L327-8896

Molecular Formula

C22H30FN7O2S (C22 H30 FN7 O2 S)

Compound Name

4-[5-(tert-butylamino)-6-(3-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazol-2-yl]-N-(2-methoxyethyl)piperazine-1-carboxamide

IUPAC name

4-[5-(tert-butylamino)-6-(3-fluorophenyl)imidazo[21-b][134]thiadiazol-2-yl]-N-(2-methoxyethyl)piperazine-1-carboxamide

SMILES

CC(C)(C)Nc1c(-c2cc(F)ccc2)nc2sc(N(CC3)CCN3C(NCCOC)=O)nn12

InChI

InChI=1S/C22H30FN7O2S/c1-22(2,3)26-18-17(15-6-5-7-16(23)14-15)25-20-30(18)27-21(33-20)29-11-9-28(10-12-29)19(31)24-8-13-32-4/h5-7,14,26H,8-13H2,1-4H3,(H,24,31)

InChI Key

QTSJFQAEMNNAOC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27245998

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

475.59

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.918

Distribution Coefficient, logD

3.918

Water Solubility, LogSw

-3.93

Polar Surface Area

68.835

Acid Dissociation Constant (pKa)

15.96

Base Dissociation Constant (pKb)

3.93

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

50.00

L327-8896 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L327-8896 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L327-8896?
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What is the minimum amount of L327-8896 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L327-8896
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L327-8896
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L327-8896 available by request