L328-0349 Screening compound: 1-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinyl)-N~3~-[3-(1-pyrrolidinyl)propyl]-3-piperidinecarboxamide

L328-0349 Screening compound: 1-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinyl)-N~3~-[3-(1-pyrrolidinyl)propyl]-3-piperidinecarboxamide
L328-0349 Screening compound: 1-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinyl)-N~3~-[3-(1-pyrrolidinyl)propyl]-3-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L328-0349
1-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinyl)-N~3~-[3-(1-pyrrolidinyl)propyl]-3-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L328-0349

Molecular Formula

C19H31N5O3 (C19 H31 N5 O3)

Compound Name

1-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-4-pyrimidinyl)-N~3~-[3-(1-pyrrolidinyl)propyl]-3-piperidinecarboxamide

IUPAC name

1-(13-dimethyl-26-dioxo-1236-tetrahydropyrimidin-4-yl)-N-[3-(pyrrolidin-1-yl)propyl]piperidine-3-carboxamide

SMILES

CN(C(C=C(N1C)N(CCC2)CC2C(NCCCN2CCCC2)=O)=O)C1=O

InChI

InChI=1S/C19H31N5O3/c1-21-16(13-17(25)22(2)19(21)27)24-12-5-7-15(14-24)18(26)20-8-6-11-23-9-3-4-10-23/h13,15H,3-12,14H2,1-2H3,(H,20,26)/t15-/m0/s1

InChI Key

GJUJDSJXIFFCNE-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD27246151

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

377.49

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

0.320

Distribution Coefficient, logD

-2.771

Water Solubility, LogSw

-1.01

Polar Surface Area

64.261

Acid Dissociation Constant (pKa)

15.00

Base Dissociation Constant (pKb)

10.49

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

73.68

L328-0349 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L328-0349 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L328-0349?
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What is the minimum amount of L328-0349 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L328-0349
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L328-0349
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L328-0349 available by request